Snapka, Robert M.
The SV40 Replicon Model for Analysis of Anticancer Drugs - 1st ed. - USA : Academic Press, 1996. - 193 p. ; - Biotechnology intelligence unit. .
This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments. Key Features * Presents unique advantages of SV40 as an experimental system for the study of classes of anticancer drugs * Details new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication * Provides details to help the reader design and interpret similar experiments.
0126536309 (hardcover) 9780126536300 (hardcover)
SV40 (Virus)
Viral genetics
DNA-drug interactions
Genetics
616.994061 Snapka 15256 1st 1996 Genetics
The SV40 Replicon Model for Analysis of Anticancer Drugs - 1st ed. - USA : Academic Press, 1996. - 193 p. ; - Biotechnology intelligence unit. .
This book provides the most up-to-date review of the simian virus 40 (SV40) minichromosome as a model for the mammalian chromosome in studies of DNA replication. It focuses on disruption of DNA replication by anticancer drugs and DNA-damaging agents. There is a strong emphasis on the unique advantages of SV40 as an experimental system for the analysis of these classes of anticancer drug mechanisms. The new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication are covered in detail to aid readers in designing and interpreting similar experiments. Key Features * Presents unique advantages of SV40 as an experimental system for the study of classes of anticancer drugs * Details new high-resolution gel electrophoresis methods for the analysis of SV40 DNA replication * Provides details to help the reader design and interpret similar experiments.
0126536309 (hardcover) 9780126536300 (hardcover)
SV40 (Virus)
Viral genetics
DNA-drug interactions
Genetics
616.994061 Snapka 15256 1st 1996 Genetics