Khalid Pervaiz

Anthelmintic Efficacy Of Melia Azedarach Linn. Oxfendazole, Febantel And Thiophanate Against Gastro-Intestinal - 1991

The present project was designed with the objective to test the anthelinintic efficacy of Helia azedarach Linn. against Trichostrangylids infection in sheep.

During the first phase of study anthelmintic efficacy of Melia azedarach Linn, fruit was tested at different dosage levels but anthelmintic efficacy was not observed at the dosage levels of 10mg to 1gm per kg body weight. Seeds of Melia azedarach were also tested for their antheirnintic efficacy but no anthelmintic effect was observed at the dosage levels of 10mg to 40mg per kg body weight. It was concluded in the first phase of study that Melia azedarach Linn. fruit and seed have no anthelmintic effect against G.I.T nematodes (Trichostrongylids) infection in sheep. During the second phase of this project clinical trials were conducted to test the anthelmintic efficacy of Melia azedarach Linn (fruit), Qxfendazole (systamex) Febantel (Rintal), and thiophanate (Nemafax) against the Trichostrongylids infection in sheep under field conditions. Results of second experiment confirmed the zero percent anthelmintic efficacy of Nelia azedarach Linn. (fruit) at the dosage level of 1gnj./kg body weight in sheep.Anthelmintic efficacy of Oxfendazole (4.5 mg/kg) Febantel (5mg/kg) and thiphanate (50mg/kg) was observed to be 100% 99.43% and 96.32% respectively against G.I.T. nematodes infection in sheep



Department of Clinical Medicine & Surgery

0223,T


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