Muti Ur Rehman Khan

Effect Of Two Anticoccidials With And Without Supplementation Of Vitamins On Some Liver And Kidney Functions - 1998

The project was designed to study the effect of anticoccidials (Ampisol 20% and Esb3 30%) with and without supplementation of vitamins on some liver and kidney functions of broiler chicken. A total of hundred day old broiler chicks were randomly divided into five equal groups designated as A, B, C, D and E. Group A was medicated with Ampisol 20% at the dose rate of 3 gm/10 liters. Group B was given Ampisol 20% alongwith supplementation of Symodek at the dose rate of 1 gmJ2 liters. Group C was medicated with Esb3 30% while group D was Esb3 30% plus Symodek. Group E was non- medicated control. Serum samples were collected randomly from five birds in each group on day 21, 28, 35 and 42 and were stored at -20°C uptil tests. The experimental period was 42 days. Estimation of alanine aminotransferase, aspartate aminotransferase, serum creatinine and serum uric acid was made by using commercially available kits in collected serum samples of all groups.

The statistical analysis of alanine aminotransferase, aspartate aminotransferase, serum creatinine showed no significant difference among groups A, B, C, D and Eon 21, 28,35,42 day of experiment. Serum uric acid levels showed no significant difference in different groups on 21 and 42 day. On day 28 of the experiment there was no significant difference between mean serum uric acid levels of group C and D but were significantly different from groups A, B and E. The mean uric acid levels of groups A, B and E were significantly different from each other. On day 35 there was significant difference among different groups except between B and C groups. As there were no adverse effects on liver and kidney functions of broiler chickens, the administration of Ampisol 20% and Esb3 30% with and without vitamins is recommended for chemoprophylaxis of coccidiosis in broiler chickens.



Department of Pathology

0576,T


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