Asim Khalid Mahmood
Studies On Duration Of Maternally Derived Antibodies Against Pasteurella Multocida In Cow Calves - 1999
Haemorrhagic septicaemia, an important bacterial disease of buffaloes and cattle results due to infection of Pasteurella multocida. Undoubtedly improved management practices and regular vaccination programme has significantly contributed to lowering the incidence of the disease in our country, however, presently the outbreaks are mostly experienced in young animals, especially, calves (Sheikh et at., 1996). The present project was designed to have an idea regarding the actual period for which maternally derived antibodies were able to afford protection against any possible challenge of the infection. The study was conducted on thirty pregnant, randomly selected Sahiwal breed of cattle, maintained at Livestock Production and Research Institute, Okara. The serum samples of the vaccinated pregnant cows were collected before parturition and before the feeding of colostrum to young one. The serum samples of the calves were collected once before taking colostrum immediately after parturition and the subsequent samples were collected six hours, 72 hours, 15 days, 30 days, 45 days and 60 days after consuming colostrum. The processing of the samples for the detection of specific antibodies against P. multocida was carried out through Indirect Haemagglutination. As the dams were vaccinated they showed a high antibody titre.
The starting result was the presence of antibodies in the serum of calves without the consumption of colostrums indicating the transfer of antibodies through the placenta from the dam's blood to the calf. The highest titre in the calves was recorded between 15 to 30 days of life and ultimately it dropped to zero at the age of 60 day after the consumption of colostrums.
Department of Microbiology
0625,T
Studies On Duration Of Maternally Derived Antibodies Against Pasteurella Multocida In Cow Calves - 1999
Haemorrhagic septicaemia, an important bacterial disease of buffaloes and cattle results due to infection of Pasteurella multocida. Undoubtedly improved management practices and regular vaccination programme has significantly contributed to lowering the incidence of the disease in our country, however, presently the outbreaks are mostly experienced in young animals, especially, calves (Sheikh et at., 1996). The present project was designed to have an idea regarding the actual period for which maternally derived antibodies were able to afford protection against any possible challenge of the infection. The study was conducted on thirty pregnant, randomly selected Sahiwal breed of cattle, maintained at Livestock Production and Research Institute, Okara. The serum samples of the vaccinated pregnant cows were collected before parturition and before the feeding of colostrum to young one. The serum samples of the calves were collected once before taking colostrum immediately after parturition and the subsequent samples were collected six hours, 72 hours, 15 days, 30 days, 45 days and 60 days after consuming colostrum. The processing of the samples for the detection of specific antibodies against P. multocida was carried out through Indirect Haemagglutination. As the dams were vaccinated they showed a high antibody titre.
The starting result was the presence of antibodies in the serum of calves without the consumption of colostrums indicating the transfer of antibodies through the placenta from the dam's blood to the calf. The highest titre in the calves was recorded between 15 to 30 days of life and ultimately it dropped to zero at the age of 60 day after the consumption of colostrums.
Department of Microbiology
0625,T