Arfan Ahmad
Comparative Immunogenicity Of Different Hydropericardium Syndrome (Hps) Vaccines In Broiolers - 2002
Formaldehyde inactivated hydro-pericardium syndrome (HPS) vaccine without any adjuvant (F-HPS), an oil based HPS vaccine (0- HPS) and alum precipitated HPS vaccine (A-HPS) were prepared and comparative immunogenicity was evaluated in broilers. These vaccines were injected to each bird of groupG1, 02 and G3 sub-cutaneously on 14t day of their age, respectively while the birds of group G4 were kept non-HPS vaccinated control. Each of the bird of each group was also vaccinated against Newcastle disease virus-NDV (LaSota strain: eye droppings) while birds of group G5 served as ND non vaccinated control.
Each of the vaccine induced detectable level of anti-HPS virus indirect haemagglutination (IHA) antibody titre. The 0-HPS vaccine induced higher titre ofthe anti-HPSV-IHA antibody titre that of F-HPS and A-HPS vaccines. All of the three vaccines induced resistance in the birds that showed 100% protection when were given challenge infection on 14 days post-vaccination while the birds of control group showed zero percent protection. At the time of challenge infection, anti- Newcastle disease virus haemagglutination inhibition (ND V-HI) antibody titres were same in the HPS vaccinated and un-vaccinated broilers.
It is concluded that all the vaccines induced effective immunity in the birds. The 0-HPS vaccine induced higher levels of anti-HPS virus IHA antibody titres than that of F-HPS and A-HPS vaccines. Moreover, non of the vaccine induced detectable level of immuno-modulatory effect on the anti-NDV-HI antibody titre of birds to NDV vaccine.
Department of Microbiology
0787,T
Comparative Immunogenicity Of Different Hydropericardium Syndrome (Hps) Vaccines In Broiolers - 2002
Formaldehyde inactivated hydro-pericardium syndrome (HPS) vaccine without any adjuvant (F-HPS), an oil based HPS vaccine (0- HPS) and alum precipitated HPS vaccine (A-HPS) were prepared and comparative immunogenicity was evaluated in broilers. These vaccines were injected to each bird of groupG1, 02 and G3 sub-cutaneously on 14t day of their age, respectively while the birds of group G4 were kept non-HPS vaccinated control. Each of the bird of each group was also vaccinated against Newcastle disease virus-NDV (LaSota strain: eye droppings) while birds of group G5 served as ND non vaccinated control.
Each of the vaccine induced detectable level of anti-HPS virus indirect haemagglutination (IHA) antibody titre. The 0-HPS vaccine induced higher titre ofthe anti-HPSV-IHA antibody titre that of F-HPS and A-HPS vaccines. All of the three vaccines induced resistance in the birds that showed 100% protection when were given challenge infection on 14 days post-vaccination while the birds of control group showed zero percent protection. At the time of challenge infection, anti- Newcastle disease virus haemagglutination inhibition (ND V-HI) antibody titres were same in the HPS vaccinated and un-vaccinated broilers.
It is concluded that all the vaccines induced effective immunity in the birds. The 0-HPS vaccine induced higher levels of anti-HPS virus IHA antibody titres than that of F-HPS and A-HPS vaccines. Moreover, non of the vaccine induced detectable level of immuno-modulatory effect on the anti-NDV-HI antibody titre of birds to NDV vaccine.
Department of Microbiology
0787,T