Maryam Nisar
Comparative Therapeutic Trials Against Coccidiosis In Dogs - 2005
The present project was designed to find out the prevalence of coccidiosis (Isosporiosis), to evaluate the comparative efficacy of Co-trimoxazole &Furazolidone and to study the effect of Isosporiosis on blood parameters.
For this purpose the faecal samples of two hundred dogs were examined in the Medicine laboratory, University of Veterinary and Animal Science, Lahore by direct smear method, and also concentration technique for identification of Isospora oocyst. Out of two hundred dogs thirty-six were found positive for the coccidial infection, showing the prevalence of Isosporiosis as 18%. For chemotherapeutic trials, thirty naturally infected and ten non-infected dogs were selected and divided randomly into four groups having ten dogs in each groups viz A, B, C and D. Group A was treated with Co-trirnoxazole at the dose rate of 15mg/kg (orally) and group B was treated with Furazolidone at the dose rate of 8mg/kg (orally). Group C was kept as infected non-medicated control. Group D was kept as non-infected and non-medicated control.
Faecal samples of experimental dogs were examined for OPG counts on day zero (pre-medication), 3rd, 7th and 10th day of medication and percentage reduction of oocyst was calculated. Cotrirnoxazole showed 63%, 90%and 97% efficacy whereas Furazolidone showed 63%, 89.8%and 95% efficacy on day 3, 7 and 10, respectively.
Statistical analysis of data revealed non-significant difference (P>0.05) between the groups A, B and D (-ye control) on day 7 and 10 of treatment. Based on criteria of percentage reduction in the number of oocyst in faeces, it was observed that Co-trimoxazole was the most effective (97%) followed by Furazolidone (95%) against Isosporiosis in dogs.
Haematological study revealed that the values of haemoglobin and packed cell volume were lower in groups A, B, and C as compared to non-infected control group. Whereas as a result of treatment in-group A and B the values of haemoglobin and packed cell volume gradually increased on day 3, 7 and 10 post-medication. It has been observed during the present study that Cotrimoxazole and Furazolidone showed their effect on blood parameters as a result of curing Isosporiosis.
Department of Clinical Medicine & Surgery
0922,T
Comparative Therapeutic Trials Against Coccidiosis In Dogs - 2005
The present project was designed to find out the prevalence of coccidiosis (Isosporiosis), to evaluate the comparative efficacy of Co-trimoxazole &Furazolidone and to study the effect of Isosporiosis on blood parameters.
For this purpose the faecal samples of two hundred dogs were examined in the Medicine laboratory, University of Veterinary and Animal Science, Lahore by direct smear method, and also concentration technique for identification of Isospora oocyst. Out of two hundred dogs thirty-six were found positive for the coccidial infection, showing the prevalence of Isosporiosis as 18%. For chemotherapeutic trials, thirty naturally infected and ten non-infected dogs were selected and divided randomly into four groups having ten dogs in each groups viz A, B, C and D. Group A was treated with Co-trirnoxazole at the dose rate of 15mg/kg (orally) and group B was treated with Furazolidone at the dose rate of 8mg/kg (orally). Group C was kept as infected non-medicated control. Group D was kept as non-infected and non-medicated control.
Faecal samples of experimental dogs were examined for OPG counts on day zero (pre-medication), 3rd, 7th and 10th day of medication and percentage reduction of oocyst was calculated. Cotrirnoxazole showed 63%, 90%and 97% efficacy whereas Furazolidone showed 63%, 89.8%and 95% efficacy on day 3, 7 and 10, respectively.
Statistical analysis of data revealed non-significant difference (P>0.05) between the groups A, B and D (-ye control) on day 7 and 10 of treatment. Based on criteria of percentage reduction in the number of oocyst in faeces, it was observed that Co-trimoxazole was the most effective (97%) followed by Furazolidone (95%) against Isosporiosis in dogs.
Haematological study revealed that the values of haemoglobin and packed cell volume were lower in groups A, B, and C as compared to non-infected control group. Whereas as a result of treatment in-group A and B the values of haemoglobin and packed cell volume gradually increased on day 3, 7 and 10 post-medication. It has been observed during the present study that Cotrimoxazole and Furazolidone showed their effect on blood parameters as a result of curing Isosporiosis.
Department of Clinical Medicine & Surgery
0922,T