Awais Younas

Clinico-Epidemiological And Therapeutical Studies On Coccidiosis ( Isospora ) In Dogs In And Around Lahore; - 2012

The present project was designed to find out the prevalence of coccidiosis (Isosporiosis), to
evaluate the comparative efficacy of Sulfadimethoxine and Furazolidone and to study the effect

of Coccidiosis on blood parameters.
For this purpose, the faecal samples of three hundred dogs were examined in the Medicine laboratory, University of Veterinary and Animal Sciences, Lahore by direct smear method and concentration technique. Out of three hundred dogs, forty nine were found positive for coccidiosis, showing the prevalence of 16.33%. For the chemotherapeutical trials, forty five naturally infected and fifteen non-infected were selected and divided randomly into four groups having fifteen dogs in each group wise A, B, C and D. Group A was treated with Sulfadimethoxine at the dose rate of 60 mg/kg (orally). Group B was treated with Furazolidone at the dose rate of 20 mg/kg (orally). Group C was kept as infected non-medicated control. Group D was kept as non-medicated and non-infected control.
The faecal samples of experimental dogs were examined for OPG (oocyst per
gram) counts on zero day (pre-medication), 3rd day, th day, and 14th day medication and percentage reduction of oocysts was' calculated. Sulfadimethoxine showed 66.69%,90.89% and 98.29% efficacy and Furazolidone showed 63.95%,
88.78% and 96.64% efficacy on 3rd, th and 14th day, respectively.
Haematological study showed that the values of haemoglobin, packed cell
volume and total erythrocyte count were lower in groups A, Band C as compared to non-infected control group. The values of total leucocyte count were higher in group A, B and C' as compared to non-infected group. As a result of treatment in group A and B, the values of haemoglobin, packed cell volume and total erythrocyte gradually increased while that of total leucocyte count gradually decrease on day 3rd ,7111 and 14th post-medication. It has been observed during the present study that sulfadimethoxine and Furazolidone showed their effect on blood parameters as a result of coccidiosis.



Department of Clinical Medicine & Surgery

1389,T


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