Arsalan Maqbool

Socio-Demographic Rick Factors Of Dengue Fever In Infected Patients Visiting Tertiary Care Center In Lahore - 2012

Dengue fever is a mosquito-borne viral infection, caused by positive strain RNA virus, genus Flavivirus. The four serotypes of dengue virus are DEN-1, DEN-2, DEN-3, and DEN-4. It is a severe flu like illness. Incubation period is 4-7 days and more severe form is dengue hemorrhagic fever (DHF) and dengue shock syndrome (DSS). 50–100 million patients of dengue infection occur annually of which 250,000 progress to DHF/DSS resulting in 24,000 deaths.
This study was conducted for the purpose to detect the dengue virus in animals of dengue fever endemic area and investigate the maintenance host of dengue virus. A total of 462 blood samples were collected randomly from different species of domestic (Buffalo, Cattle, Sheep, Goat), draught (Horse, Donkey), pet (Cat, Dog), poultry (back yard poultry), and wild animals (Monkey), in the areas hit by dengue from Lahore during August 2011 to November 2011)
The conformation of dengue infection in animal was performed by using NS-1, IgG and IgM ELISA. Results revealed that among monkeys and dogs dengue was positive in 64.71% (n=11) and 21.05% (n=20) respectively identified by IgM ELISA. Not a single animal was found positive for dengue by using NS-1 and IgG ELISA. Hence there is a need to work on determination of maintenance host of dengue fever virus in our set up and the need exists to further explore the certain aspects related to dengue and its spread. Although due to resources constraints this study provides very limited but elaborated results for further work in this domain.



Department of Epidemiology & Public Health

1557,T


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