Muhammad Javed Raza

Immunomodulatory Effect Of Hing (Ferula Foetida) Along With Infectious Bursal Disease (Ibd) Vaccine In Broiler - 2016. - 46p.;

A number of feed additives including antibiotics have been extensively used in
poultry feeds. However, the use of antibiotics has been restricted due to the drug resistance
and the issue of residues in meat. Now a day, the use of medicinal plants is being popular as
an alternate remedy. Asafoetida is a natural feed additive and antimicrobial, immune
stimulator, antiviral, antifungal, anti-parasitic, antithrombotic, antioxidant, anti-cancerous,
and vasodilator activities. It is being used for the control of some viral problems. Some
previous studies also indicated that it has beneficial effects on the immune system. Therefore,
the present study was designed to estimate the immunomodulatory effects of F. foetida with
IBD vaccine in enhancing the immune system and ultimately increase the production of
poultry products.
A total of n=90 day old broiler chicks were purchased and kept under the optimum
conditions at CVAS Jhang. Birds were divided into three groups A, B, C and group B and C
were further divided into three subgroups (B1, B2, B3 and C1, C2, C3). Group A was treated
as positive control group and was administered with commercially available IBD and ND
vaccine and routine diet while group B was administered with asafoetida at the rate of 2%,
4%, and 6% along with vaccine to see the impact of different levels of asafoetida on the
immune system and to see the effects (if any) of various doses of asafoetida. Group C was
only administered with asafoetida in feed at the same rate as to group B. At the end of study
birds were slaughtered to observe the effects of asafoetida administration.
Positive effect of asafoetida has been reported by many studies. F. foetida is a
medicinal herb used for the prevention and treatment of many diseases, because of having
antiviral, antibacterial and antifungal activities. Also act as a good growth promoting agent
and have beneficial effects on the immune system. So, it was hypothesized that the present
study was helpful to determine the immunomodulatory effect of asafoetida for commercially
available IBD vaccine and could reduce the cost of vaccination for commercial poultry

Department of Pathology
Dr. Muhammad Asif Idrees
Dr. Iahtasham Khan


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