Study Of Hematological Alterations And Chemotherapeutic Trials Of Camels Naturally Infected With Trypanosomiasis In Cholistan, Bahawalpur (Record no. 10593)
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| fixed length control field | 04059nam a22002297a 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20170301093958.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 170301b2016 xxu||||| |||| 00| 0 eng d |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 2668-T |
| 100 ## - MAIN ENTRY--AUTHOR NAME | |
| Personal name | Zubair Bashir (2014-VA-782) |
| 110 ## - MAIN ENTRY--CORPORATE NAME | |
| Location of meeting | Prof. Dr. Aneela Zameer Durrani |
| 245 ## - TITLE STATEMENT | |
| Title | Study Of Hematological Alterations And Chemotherapeutic Trials Of Camels Naturally Infected With Trypanosomiasis In Cholistan, Bahawalpur |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Year of publication | 2016. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Number of Pages | 49p.; |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Trypanosoma evansi (T. evansi) is a flagellated protozoan that is mechanically spread through biting flies like Stomoxys, Tabanus and Lyperosia.T. evansi was first isolated in 1880 from diseased equines and camels of Indian sub-continent. It is the parasite of likewise intravascular as well as extra vascular fluids causing “surra” in the subtropical and tropical regions all over the world, including Africa, Asia, and America. It affects a wide range of mammals. It is mostly observed in camelids and equines but camel is the principal host. Trypanosomiasis in Pakistan is prevalent as a major threat to the camels causing heavy financial losses like causing anemia, weight loss, high fever, anorexia, dullness, depression, pale mucous membranes, facial paralysis, and thin hump dropped to one side, abortion in females and even death of camels.Considering the significance and utilization of camels in our country and the substantial losses rendered by trypanosomiasis, the present study was designed to study incidence, hematological alterations and chemotherapy of trypanosomiasis in camels of Bahawalpur district. For this purpose, 100 camels were examined for Trypanosoma infection. The blood was collected by ear-tip puncture and from Jugular venipuncture. Then thin blood smear slide was prepared and dried up in air and stained with Geimsa's staining method and examined under microscope. Trypanosomes were identified by their morphological characteristics (Chandler and Read, 1961), as described by standard texts like Taylor et al. (2007). Overall incidence of T. evansi in camels was estimated as 20%. The effect of trypanosomiasis on various blood parameters (Hb, ESR, TEC, TLC, DLC, and PCV) was determined in 30 camels including 15 apparently healthy and 15 trypanosome infected camels to compare normal blood parameters. The remarkable decrease in Hb, TEC, PCV, platelets and lymphocytes were observed while remarkable increase inESR and TLC was observed.Severe leukocytosis, neutrophilia, monocytosis, eosinophilia and basophilia were also observed in diseased camels. For chemotherapy, 12 camel’s positive for trypanosomiasis, were divided into three groups (A, B and C). The animals of group A were treated with Imidocarb dipropionate @ 1.2 mg Kg-1 BW I/M, and efficacy of drug was found 50% in camels against trypanosomiasis. The group B was treated with Buparvaquone @ 3 mg/kg BW 1/M and was observed 25% effective. While the group C was treated with Isometamedium chloride(Trypamidium Samorin®, Merial, Pakistan) @ 0.75mg/kg BW I/M, which was found 100% effective. The efficacy of drugs was measured on the basis of disappearance of clinical signs and recovery rate of the animals, and blood smear examination at day 2, 4 and 07 of post-medication. Finally, the data on hematology were analyzed by Student's T-test using statistical software package SPSS v22 (statistical package for social science), P < 0.05 was considered significant. Considering the significance and utilization of camel in our country and the substantial losses rendered by trypanosomiasis, the present project was designed to record clinical cases and chemotherapy of trypanosomiasis in camels of Bahawalpur districts. The results of this study will help farmers and veterinary practitioners in field. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Clinical Medicine --CMS |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Clinical Medicine and Surgery |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dr. Khalid Mehmood |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dr. Muhammad Avais |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dr. Haroon Akbar |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Thesis |
| Damaged status | Collection code | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Accession Number | Koha item type |
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| Veterinary Science | UVAS Library | UVAS Library | Thesis Section | 2017-03-01 | 2668-T | 2668-T | Thesis |