Effect Of Unilateral And Bilateral Thyroidectomy On Hormonal And Biochemical Parameters In Dogs (Record no. 10604)

000 -LEADER
fixed length control field 02423nam a22002177a 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20170302085650.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 170302b2016 xxu||||| |||| 00| 0 eng d
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 2657-T
100 ## - MAIN ENTRY--AUTHOR NAME
Personal name Mehmood Ur Rehman (2009-VA-177)
110 ## - MAIN ENTRY--CORPORATE NAME
Location of meeting Dr. Hamid Akbar
245 ## - TITLE STATEMENT
Title Effect Of Unilateral And Bilateral Thyroidectomy On Hormonal And Biochemical Parameters In Dogs
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Year of publication 2016.
300 ## - PHYSICAL DESCRIPTION
Number of Pages 57p.;
502 ## - DISSERTATION NOTE
Dissertation note Thyroid gland is one of the most important endocrine gland of animal body. T3 and T4 are two major hormones secreted by thyroid gland. These hormones have a major role in metabolism of cells and organs. In normal thyroid both these hormones have anabolic effect. Thyroid tumors account for 1.2-3.8 % of all types of tumors in dogs. Unilateral, bilateral or subtotal thyroidectomies are practiced to remove benign or malignant thyroid carcinomas.
The present study was conducted on 12 mongrel dogs. These dogs were rendered to 3 groups with 4 dogs in each group. One group acted as control, in which no surgery was performed, second group underwent unilateral removal of thyroid gland while the third group underwent bilateral removal of thyroid gland. Free thyroxine, thyroid stimulating hormone level, calcium, W.B.Cs, R.B.Cs and haemoglobin concentration were monitored for 21 days post-operatively.
The data was expressed as mean and standard deviation. Results of the study were analysed by 2 samples T-test, one way ANOVA using multiple comparison test on SPSS version 16.0.
Based on these results it was concluded that bilateral thyroidectomy was effective in relieving hyperthyroidism but there is a need to immediately initiate levothyroxine therapy. Free T4 level drops near to zero by day 21 and TSH level rises by many folds. On the other hand, in unilateral procedure Free T4 level remain in normal range and 75% of dogs require no levothyroxine therapy. Level of calcium in unilateral and bilateral thyroid removal remains within normal range provided parathyroid glands are preserved properly. Haemoglobin concentration in both the procedures is reduced significantly postoperatively. There is a need to monitor blood parameters postoperatively.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term Veterinary Surgery
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term CMS--Clinical Medicine and Surgery
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Prof. Dr.M.Arif Khan
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Dr. Muti ur Rehman Khan
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Thesis
Holdings
Damaged status Collection code Permanent Location Current Location Shelving location Date acquired Full call number Accession Number Koha item type
  Veterinary Science UVAS Library UVAS Library Thesis Section 2017-03-02 2657-T 2657-T Thesis


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