A Clinico-Biochemical Study On Different Pre-Anesthetic Drugs With Propofol For Neutering In Dogs (Record no. 10799)
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fixed length control field | 03107nam a22002177a 4500 |
005 - DATE AND TIME OF LATEST TRANSACTION | |
control field | 20170403100747.0 |
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
fixed length control field | 170403b2016 xxu||||| |||| 00| 0 eng d |
041 ## - LANGUAGE CODE | |
Language code of text/sound track or separate title | eng |
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
Classification number | 2689-T |
100 ## - MAIN ENTRY--AUTHOR NAME | |
Personal name | Saba Siddique |
110 ## - MAIN ENTRY--CORPORATE NAME | |
Location of meeting | Dr. Sadaf Aslam |
245 ## - TITLE STATEMENT | |
Title | A Clinico-Biochemical Study On Different Pre-Anesthetic Drugs With Propofol For Neutering In Dogs |
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
Year of publication | 2016. |
300 ## - PHYSICAL DESCRIPTION | |
Number of Pages | 45p.; |
502 ## - DISSERTATION NOTE | |
Dissertation note | The present research project was designed to study the effect of three routinely used pre anaesthetic (alpha-2 adrenergic agonists) drugs xylazine (xylaz; 20 mg/ml, farvet, Holland) and medetomidine (doiter, 1 mg/ml ; Orion pharma, finland), diazepam(Valium 0.25 mg/kg) and propofol (pofol, 10 mg/ml ;Dongkook pharma, korea) anaesthesia in male dogs and castration surgery was performed using pre scrotal approach. The effect of these sedative and anaesthetic agents was studied at physical (temperature, pulse, and respiration), sedative (palpebral effect), analgesic (tail pinch, toe pinch reflex), liver function (ALT, AST, and ALP), renal functions (serum creatinine, BUN) and haematological (RBC, WBC, Hb) parameters. A total number of twelve (12) dogs (mix breed) clinical cases were selected. These dogs were subjected into three groups (A, B , C) each comprising four (4) dogs. Different drugs combination was administered in each group of dogs. Three different drug combinations are; Group A .Xylazine-Propofol Group B. Diazepam-Propofol Group C. Medetomidine-Propofol Blood samples were taken at four different intervals like 0 minutes, 30 minutes, 60 minutes and after 24 hours in EDTA coated vacutainer for studying haematological parameters and in lithium heparin vacutainer for evaluating biochemical parameters. Results revealed that both sedative and anaesthetic agents produce slight non-significant changes in liver enzymes but in case of renal function test, medetomidine-propofol produce significant Summary 42 changes in serum creatinine and xylazine-propofol, and diazepam-propofol produce significant changes in the values of blood urea nitrogen. Coming towards haematology, white blood cells increase significantly in diazepam-propofol receiving group. The results of the present research study were mostly similar with the findings of other scientists. The results of present project were analysed by ANOVA followed by Turkey honestly significant difference (HSD) test. Conclusion The result of present project will prove fruitful for veterinary practioners for selectin anaesthesia protocol for patients suffering from hepatitis or other liver, renal and haematological problems and would be productive to solve the problems of anaesthetists who are actively engaged in canine practice all over the world. On the basis of findings of this study it is concluded that medetomidine-propofol combination gives better results. |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical Term | Surgery |
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
Topical Term | CMS--Clinical Medicine and Surgery |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Prof. Dr.M.Arif Khan |
700 ## - ADDED ENTRY--PERSONAL NAME | |
Personal name | Dr. Raheela Akhtar |
942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
Koha item type | Thesis |
Damaged status | Collection code | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Accession Number | Koha item type |
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Veterinary Science | UVAS Library | UVAS Library | Thesis Section | 2017-04-03 | 2689-T | 2689-T | Thesis |