| 000 -LEADER |
|---|
| fixed length control field |
01681nam a2200217 a 4500 |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| ISBN |
0521836549 (hardcover) |
| 020 ## - INTERNATIONAL STANDARD BOOK NUMBER |
|---|
| ISBN |
9780521836548 (hardcover) |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
572.8 Henderson 17928 1st 2005 Genetics |
| 100 ## - MAIN ENTRY--AUTHOR NAME |
|---|
| Personal name |
Henderson, Brian. |
| 245 10 - TITLE STATEMENT |
|---|
| Title |
Molecular Chaperones And Cell Signalling |
| 250 ## - EDITION STATEMENT |
|---|
| Edition statement |
1st ed. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Place of publication |
USA: |
| Name of publisher |
Cambridge University Press, |
| Year of publication |
2005. |
| 300 ## - PHYSICAL DESCRIPTION |
|---|
| Number of Pages |
344 p. ; |
| 520 ## - SUMMARY, ETC. |
|---|
| Summary, etc |
Originally published in 2005, this book reviews understanding of the biological roles of extracellular molecular chaperones. It provides an overview of the structure and function of molecular chaperones, their role in the cellular response to stress and their disposition within the cell. It also questions the basic paradigm of molecular chaperone biology - that these proteins are first and foremost protein-folding molecules. Paradigms of protein secretion are reviewed and the evolving concept of proteins (such as molecular chaperones) as multi-functional molecules for which the term 'moonlighting proteins' has been introduced is discussed. The role of exogenous molecular chaperones as cell regulators is examined and the physiological and pathophysiological role that molecular chaperones play is described. In the final section, the potential therapeutic use of molecular chaperones is described and the final chapter asks the question - what does the future hold for the extracellular biology of molecular chaperones? |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Cellular signal transduction |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Protein folding |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Cellular signal transduction |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Henderson, Brian. |
| 700 1# - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Pockley, A. Graham. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Books |
