Effect Of Sub Chronic Exposure Of Low Doses Of Bisphenol A On Anthropometric Parameters And Lipid Profile In Rats (Record no. 13616)

000 -LEADER
fixed length control field 02604nam a22002057a 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20170921115048.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 170921b2017 xxu||||| |||| 00| 0 eng d
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 2868-T
100 ## - MAIN ENTRY--AUTHOR NAME
Personal name Sayeda Iqra Ahmad (2011-VA-433)
110 ## - MAIN ENTRY--CORPORATE NAME
Location of meeting Dr. Khalid Abdul Majeed
245 ## - TITLE STATEMENT
Title Effect Of Sub Chronic Exposure Of Low Doses Of Bisphenol A On Anthropometric Parameters And Lipid Profile In Rats
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Year of publication 2017.
300 ## - PHYSICAL DESCRIPTION
Number of Pages 45p.;
502 ## - DISSERTATION NOTE
Dissertation note Bisphenol A is an endocrine disruptor. It is monomer of polystyrene and a basic component of epoxy resins. It is carcinogenic in nature and has adverse impact on health of different animals as wells as human beings. It harms the reproductive, renal system as well as a basic reason of metabolic syndrome. The aim of this study is to assess the effect of sub chronic exposure of Bisphenol A on anthropometric parameters and lipid profile in rats
Bisphenol A may elevate serum lipid profile level and increase the ratio of anthropometric parameters in rats.
Forty eight albino rats half male and half females of similar age and weight were selected. They were divided into three groups each having sixteen rats in each (8 males,8 females) and named as Group A, B and C for experimental trial of three months. Group A was referred as control group treated with only basal diet and water. Group B was treated with 0.1mg/kg (body weight) BPA with basal diet and water. Group C was treated with 1mg/kg (body weight) BPA with basal diet and water. After three months blood sample was collected by euthanizing the rats to obtain serum sample for biochemical analysis and at the same time anthropometric values were noted.
Data was analyzed via two way ANOVA using SPSS software and Post hocTukey test was applied to study and compare differences between the groups. The p value <0.05 was assumed as significant value.
At the end of this trialour studies suggest thatthe effect of Bisphenol A increased the ratio of anthropometric parameters up to a certain limit as well as it significantly effects the all nutritional parameters. It highly effectsthe concentration of HDL in serum lipid profile.
It disturbs the concentration of ALP and AST at low doses while ALT had no significant effects due to BPA. It had no significant influences on kidney metabolites e.g., creatinine urea and BUN. Glucose concentrationalso not showed any profound effect in male and female albino rats.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term Physiology
710 ## - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Dr. Muhammad Shahbaz Yousaf
710 ## - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Ms. Amina Chughtai
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Thesis
Holdings
Damaged status Collection code Permanent Location Current Location Shelving location Date acquired Full call number Accession Number Koha item type
  Veterinary Science UVAS Library UVAS Library Thesis Section 2017-09-21 2868-T 2868-T Thesis


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