Comparative Efficacy Of Trypanocidal Drugs And Their Effects On Some Blood Parameters I Camels Naturally Infected With Surra (Record no. 2048)

000 -LEADER
fixed length control field 03847nam a2200205Ia 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20150916130703.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 150525s1993 xx 000 0 und d
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 0283,T
100 ## - MAIN ENTRY--AUTHOR NAME
Personal name Farrukh Jamal Nizami
110 ## - MAIN ENTRY--CORPORATE NAME
Location of meeting Muhammed Afzal
245 ## - TITLE STATEMENT
Title Comparative Efficacy Of Trypanocidal Drugs And Their Effects On Some Blood Parameters I Camels Naturally Infected With Surra
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Year of publication 1993
502 ## - DISSERTATION NOTE
Dissertation note Trypanosomiasis in camels caused by Trypanosoma evansi results in great economic losses if not treated properly. The present study had been designed to find out the prevalence and treatment of Trypanosoma evansi infection by using Naganol (sayer) and Trypacide (M & B) in camels in District Layyah. The effects of the infection and drugs on differential leukolyte count (DLC), Haemoglobin (HB) Packed Cell Volume (PCV), Erythrocytic Sedimentation Rate (ESR) and Total Serum protein were also estimated. For this purpose 1000 suspected camels were examined and 75 (7.5%) were found positive for Trypanosoma evansi infection. Out of these, 45 positive cases were randomly divided into 3 equal groups comprising 15 animals each. Two of the groups were served with two different drug trials, and the 3rd group was kept as untreated infected control. While a 4th group of 15 camels was kept as non-infected and untreated control. The results of all the aforesaid blood parameters were recorded just before and on day 21 post-treatment. The data so obtained was analysed and results were made as follows.

Out of 1000 camels, 75 were found to be harbouring the Trypanosoma evansi infection with a pevalence rate being 7.5 percent.

Naganol (Bayer) was found to be 60% Trypanocidal on day 5 and 100% on day 10 and 21 post treatment. Trypacide (M & B) was found to be 53% Trypanocidal on day 5 and 80% on day 10 and 21 post treatment.

There was marked Neutropenia with lymphocytosis before the treatment in infected versus non infected ones. The average values of Neutrophils were 38+0.62, 39±0.02, 36±0.47 and 52j0.48 in the 4 groups respectively. But on day 21 after treatment, the number of neutrophils increased in group Nos. I and II with n average of 51±0.33 and 49±1.41 while the group No. Ill and IV revealed no difference in their count. The mean values of lymphocytes prior to and after the treatment were 51±0.33, 52±0.71, 56±0.46 and 41±0.36, 42±0.40, 45.3±1.09, 56±0.46 and 39±0.23 respectively. There was 41 .66% increase in Eosinophils of group I, II and Ill before the treatment, the average being 7±0.22, 50.48 and 5±0.48 respectively, while the group No. IV possessed 4+0.19% neutrophils. The Eosinophilia tended to become normal with 33.33% decrease, average being 4+0.40 and 3+0.45 in group No. I and II respectively on day 21 post treatment; while the neutrophils count remained nearly the same in group No Ill and IV average being 6+0.24 and 4+0.19 respectively on day 21 post treatment.

The Basophils and Monocytes Count remained unchanged before and after the treatment in all the 4 groups.

Haemoglobin(Hb) and Packed Cell Viume (PCV) showed decrease on day 0, but Erythrocytic Sedimentation Rate (ESR) and Total Serum Protein were increased on day 0 in case of positive camels. On day 21 post treatment with Naganol (Bayer) and Trypacide (M & B), Haemoglobin (HB) and Packed Cell Volume (PCV) were increased in group Nos I and II. Whereas Erythrocytic Sedimentation Rate (ESR) and Total Serum Protein level were decreased on day 21 post treatment in the same groups. On the other hand the values remained unchanged in group No. IV. (Noninfected, untreated control).
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term Department of Parasitology
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Asif Rabbani
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Muhammed Sarwer Khan
710 ## - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Faculty of Veterinary Sciences
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Thesis
Holdings
Damaged status Collection code Permanent Location Current Location Shelving location Date acquired Full call number Accession Number Koha item type
  Veterinary Science UVAS Library UVAS Library Thesis Section 2015-05-26 0283,T 0283,T Thesis


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