Comparative Efficacy Of Various Antiviral Agents Avian Influenza Virus(Type H7) (Record no. 2627)

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fixed length control field 01841nam a2200193Ia 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20150921153432.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 150525s2007 xx 000 0 und d
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 0900,T
100 ## - MAIN ENTRY--AUTHOR NAME
Personal name Tahir Mahmood Shaukat
110 ## - MAIN ENTRY--CORPORATE NAME
Location of meeting Prof.Dr.Muhammad Ashraf
245 ## - TITLE STATEMENT
Title Comparative Efficacy Of Various Antiviral Agents Avian Influenza Virus(Type H7)
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Year of publication 2007
502 ## - DISSERTATION NOTE
Dissertation note In this project 3 different concentrations of each of amantadine HC1, extracts of fresh leaves of opuntia herb, papaya and dried powdered leaves of green tea in distilled water were evaluated for their antiviral activity, by injecting into 10 days old live embryonated broiler chicken eggs through chorioallantoic sac route. For each drug embryonated eggs were treated only with it's 3 different concentrations to evaluate toxicity, whereas to check antiviral efficacy, embryonated eggs were treated with suspensions of three different concentrations of drug with 4HA titre of AIV (type H7).

In case of amantadine HC1 out of 50ug/ml, 500ug/ml and l000ug/ml concentrations only 500ug/ml was found to be an ideal concentration, as in addition to stop virus growth it also did not kill the embryos. In case of Opuntia dellinii all the 3 concentrations used were not toxic for embryos, but antiviral oeffect was observed only by 4gm and 8gm/100ml concentrations. Green tea extract was found to be effective against AIV only at 8gm/100ml concentration with no damage to chick embryos. Papaya leaves extract as a whole failed to check virus replication at all the three concentrations used in this experiment i.e. 2gm, 4gm and 8gm/100ml. All these dose levels were not lethal for chick embryos.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term Department of Pharmaoclogy & Toxicology
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name ghjgh
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Prof.Dr.Khushi
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Thesis
Holdings
Damaged status Collection code Permanent Location Current Location Shelving location Date acquired Full call number Accession Number Koha item type
  Veterinary Science UVAS Library UVAS Library Thesis Section 2015-05-28 0900,T 0900,T Thesis


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