Clinico-Therapeutical And Haematological Studies On Babesiosis In And Around The Livestock Experimental Station Qadirabad in Lohi Sheep (Record no. 2646)

000 -LEADER
fixed length control field 03399nam a2200205Ia 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20150921154718.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 150525s2006 xx 000 0 und d
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 0921,T
100 ## - MAIN ENTRY--AUTHOR NAME
Personal name Asif Rashid
110 ## - MAIN ENTRY--CORPORATE NAME
Location of meeting Dr. Jawaria Ali Khan
245 ## - TITLE STATEMENT
Title Clinico-Therapeutical And Haematological Studies On Babesiosis In And Around The Livestock Experimental Station Qadirabad in Lohi Sheep
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Year of publication 2006
502 ## - DISSERTATION NOTE
Dissertation note Ovine Babesiosis is a serious haemoparasitic disease of sheep. it is caused by two hemosporidian parasites i.e. Babesia motasi and Babesia ovis, transmitted by ticks. The disease results into death due to fever, excessive destruction of RBC's, anemia, haemoglobinuria and icterus. The present study was conducted to find out the prevalence of babesiosis in Lohi sheep in and around the Livestock Experimental Station, Qadirabad and to study the effect of 2 anti-protozoan (babesicidal) drugs i.e.Diminazene diaceturate (Diminazene; star lab.) and Imidocarb dipropionate (Imizol; ICI) on the recovery and health of animal. The effect of hernosporidian parasites on various blood parameters was also studied. The parameters included: Haemoglobin (Hb) estimation and Packed Cell Volume (PCV).

For this purpose 310 Lohi sheep were examined for the presence of babesiosis. Out of 310 Lohi sheep, 30 were found positive showed 9.67% prevalence. For treatment protocol, thirty naturally infected and ten noninfected sheep were selected and divided into four groups having ten sheep in each group i.e. A, B, C and D.


Diagnosis was confirmed on the basis of blood smear method, which revealed the presence of Babesia. The parasite appeared as piriform bodies within the light pink erythrocytes.

The animals of group A were treated with diminazene (Diminazene diaceturate) at a dose rate of 3.5mg/kg body weight at zero day. Three out of ten animals recovered at 3rd day of first injection, three animals recovered at 7th day of first injection, two recovered at 10th day of first injection, while two animals did not show any improvement and might be chronically infected. This drug showed 80% efficacy at 10th day while the animals of group B were treated with Imizol (Imidocarb dipropionate) at a dose rate of 2mg /kg body weight at zero day. Six out of ten animals recovered at 3rd day of first injection, three recovered at 7th day of first injection and remaining one recovered at 10th day of first injection. This drug showed 100% efficacy at 10th day. Animals of group C were served as infected untreated control while animals of group D were served as healthy control.

Efficacy of drugs was detected by negative blood smear. Imizol gave best results where as Diminazene was second in efficacy against babesiosis.

Haematological examination revealed a significant decrease in .Hb and PCV in group A and C on 3rd, 7th and 10th day post medication as compared to group B.

From the results of present study, it has been concluded that Imidocarb dipropionate (Imizol) was the drug of choice for the treatment of ovine babesiosis in Lohi sheep when given at the dose rate of 2mg/kg body weight by intramuscular route.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term Department of Clinical Medicine & Surgery
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Dr. Javaid Iqbal
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Prof. Dr. Khalid Pervez
710 ## - ADDED ENTRY--CORPORATE NAME
Corporate name or jurisdiction name as entry element Faculty of Veterinary Sciences
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Thesis
Holdings
Damaged status Collection code Permanent Location Current Location Shelving location Date acquired Full call number Accession Number Koha item type
  Veterinary Science UVAS Library UVAS Library Thesis Section 2015-05-28 0921,T 0921,T Thesis


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