Clinico-Biochemical Studies At Variable Degree Of Jejunal Resection In Dogs (Record no. 2805)
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| 000 -LEADER | |
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| fixed length control field | 03895nam a2200193Ia 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20151001134935.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150525s2010 xx 000 0 und d |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 1089,T |
| 100 ## - MAIN ENTRY--AUTHOR NAME | |
| Personal name | Muhammad Sohail Dilawer |
| 110 ## - MAIN ENTRY--CORPORATE NAME | |
| Location of meeting | Prof.Dr.Muhammad Arif Khan |
| 245 ## - TITLE STATEMENT | |
| Title | Clinico-Biochemical Studies At Variable Degree Of Jejunal Resection In Dogs |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Year of publication | 2010 |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | The present study was designed to evaluate the effects of jejunectomy; indicated in case of necrosis, devitalization, malignancy, and evidence of foreign body and trauma in jejunum. A total of 20 mongrel dogs were selected which underwent a clinical evaluation to be termed physiologically normal. These were divided into four groups A, B, C, D designated for 70% jejunal resection, 80% jejunal resection, 100% jejunal resection and control without resection respectively. The dogs within the groups were evaluated on 15, 30, 45, 60, 75 and 90 days post-operative for various blood parameters, serum sodium, potassium, chloride and bicarbonate ions, body weight and fecal consistency. After the study, dogs were euthanized and postmortem was conducted to observe and analyze the changes associated with the respected portion Regain in body weight was evident in group A, B but it was very slow in group C. Fecal consistency became soft and firm on day 15 in group A, B and on day 45 in group C . No effect between jejunectomized groups and control without jejunectomy was observed for chloride, potassium and bicarbonate ions. However, significant difference was observed for sodium ions indicating low serum sodium levels for jejunectomized group compared control. The WBCs levels were significant in all jejunectomized groups compared to normal indicating higher WBCs in the former groups. Granulocytes and lymphocytes were also higher in group A, C and Group B respectively as compared to D at the 90 day the study. Red blood cells, hemoglobin, PCV, MCH, MCHC values were significant at various days of study period between the different groups but their values were within the normal range indicating the blood parameters reversion to normalcy. For platelets, the values were also in the normal range in the studied groups when compared with control. A total number of 3 dogs died during the study, all of them from jejunectomized groups. At the end of experiment, the dogs euthanized for postmortem findings depicted no abnormal condition at the anastamotic site and in abdominal cavity. CONCLUSION: The study indicated that after the surgical procedure of jejunectomy, the dogs tend to reinvigorate their blood physiological parameters and serum ions. Three dogs died out of 15 jejunectomized thereby indicating that there is a probability of postoperative complication, which in that case was strangulation and torsion. Regain in body weight was the slowest in group C indicating the loss of nutrients essential for maintaining body weight. Therefore it is better to go far 700/G resection and 80% resection. RECOMMENDATIONS: Further research regarding the various aspects necessary for maintaining health should be studied before coming to a decision about the percentage of resection performed. The metabolic problems that may arise due to removal of jejunum and loss of nutrients because of loss of absorptive capacity needs to be studied and standardized in this regard. Post operative care and duration of study for experiments should be increased to observe changes in physiological parameters with the passage of time. Other parameters like Liver Function Tests, Kidney Function Tests be studied and clinical nutrition trials be conducted so as to counter the negative effects of jejunectomy. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Department of Clinical Medicine & Surgery |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Mr.Shahan Azeem |
| 710 ## - ADDED ENTRY--CORPORATE NAME | |
| Corporate name or jurisdiction name as entry element | Faculty of Veterinary Sciences |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Thesis |
| Damaged status | Collection code | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Accession Number | Koha item type |
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| Veterinary Science | UVAS Library | UVAS Library | Thesis Section | 2015-05-27 | 1089,T | 1089,T | Thesis |