| 000 -LEADER |
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| fixed length control field |
02074nam a2200181Ia 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION |
|---|
| control field |
20151001145609.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION |
|---|
| fixed length control field |
150525s2010 xx 000 0 und d |
| 041 ## - LANGUAGE CODE |
|---|
| Language code of text/sound track or separate title |
eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER |
|---|
| Classification number |
1213,T |
| 100 ## - MAIN ENTRY--AUTHOR NAME |
|---|
| Personal name |
Sadia Abrar |
| 110 ## - MAIN ENTRY--CORPORATE NAME |
|---|
| Location of meeting |
Dr. Muhammad Ovais Omer |
| 245 ## - TITLE STATEMENT |
|---|
| Title |
Effect Of Strawberry Juice On Angiogenesis Using Chorioallantoic Membrane (Cam) Assay |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) |
|---|
| Year of publication |
2010 |
| 502 ## - DISSERTATION NOTE |
|---|
| Dissertation note |
Angiogenesis, the formation of new blood vessels, is a hallmark of almost all neoplastic and non-neoplastic degenerative diseases. Targeting angiogenesis with natural antiangiogenic compounds may lead to safe, effective and low cost budget therapies. Strawberries provide various vital natural substances which have a significant role in human health and disease prevention. In our study, we have focused on the effect of strawberry juice on angiogenesis using chicken chorioallantoic membrane (CAM) assay. Fresh fertilized eggs were taken, sprayed with 70% ethanol and incubated at 37 °C (humidity 55-60%). At day 5 of incubation a small window was made on each egg, 4-5 ml of albumen was removed, windows were sealed with sterile parafilm and eggs were returned to incubator. Strawberry juice was obtained from fully ripened strawberry fruits and various dilutions were prepared in distilled water. Filtered dilutions of the juice were used for experimental analysis and applied to the CAMs on day 6. of incubation. Macroscopic vascular changes were evidently observed among all treated CAMs on day 7 of incubation. Reduction in the total area and diameter of primary, secondary and tertiary blood vessels was observed after treatment with strawberry juice in concentration dependent manner. By using SPIP software 3D surface roughness measurements were carried out which clearly elaborated antiagiogenic effect of strawberry juice on CAMs. Strawberry juice inhibits angiogenesis, which is a common denominator shared by various major disease.
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| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM |
|---|
| Topical Term |
Department of Pharmaoclogy & Toxicology |
| 700 ## - ADDED ENTRY--PERSONAL NAME |
|---|
| Personal name |
Prof. Dr. Muhammad Ashraf |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) |
|---|
| Koha item type |
Thesis |
