Immuo-Pathological Response Of Pigeons To Challenge Infection Of Newcastle Disease Virus (Ndv) (Record no. 2947)

000 -LEADER
fixed length control field 02823nam a2200181Ia 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20151001150237.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 150525s2011 xx 000 0 und d
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 1228,T
100 ## - MAIN ENTRY--AUTHOR NAME
Personal name Yasir Amin
110 ## - MAIN ENTRY--CORPORATE NAME
Location of meeting Dr. Asim Aslam
245 ## - TITLE STATEMENT
Title Immuo-Pathological Response Of Pigeons To Challenge Infection Of Newcastle Disease Virus (Ndv)
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Year of publication 2011
502 ## - DISSERTATION NOTE
Dissertation note This study trial was designed to evaluate and compare the efficacy of two locally available live Newcastle disease vaccines (Medivac ND LaSota and VRI, Mukteshwar ND vaccine), also to compare two routes (Oral and Ocular) of vaccine administration in term of antibody titre and assessment of protection against field (chicken) isolated virulent Newcastle virus challenge (NDV) in pigeons. Study of clinical signs, gross and histopathological lesion in different organ of non-vaccinated and challenged birds was also the part of our present study. For this purpose one hundred and twenty pigeons were purchased from the local market and screened for Newcastle disease antibodies using Hemagglutination inhibition test. Healthy pigeons were randomly divided into six groups i.e. A, B, C, D, E and F, comprising 20 birds each. Group E and F were kept as positive and negative Control respectively. Group A and C were vaccinated with Medivac ND LaSota vaccine at day 7th and 21st of experiment through oral and ocular route. Similarly Group B and D were immunized with VRI (Mukteshwar) ND vaccine through oral and ocular route respectively. At 28th day of experiment all the groups except group F were challenged with velogenic field isolate of NDV at a dose rate of 0.1 ml through ocular route. Serum samples were collected at day 14, 21, 28, 35 and 42 of experiment for the determination of antibody titre. Post-infection clinical signs in control positive group were i.e. anorexia, dullness, depression, decreased feed intake, discharge from mouth, greenish diarrhea, nervous manifestations, leg and wing paralysis. Gross lesions on different organs were hemorrhages in trachea, proventriculus, spleenomegaly and greenish intestinal contents. Medivac ND LaSota vaccine produced higher immune response in term of antibody titre as compared to VRI (Mukteshwar) ND vaccine. It was also observed that ocular route irrespective to vaccine type produced significantly (P<0.05) higher immune response than oral route. Vaccine strains used in this study efficiently induced immune response through ocular route, suggesting that implementation of this vaccination programs in future may prevent ND outbreaks in pigeons, especially in racing pigeons, and may prevent NDV spread to other avian species, mainly poultry.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term Department of Pathology
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Prof. Dr. Muhammad Younus Rana
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Thesis
Holdings
Damaged status Collection code Permanent Location Current Location Shelving location Date acquired Full call number Accession Number Koha item type
  Veterinary Science UVAS Library UVAS Library Thesis Section 2015-05-28 1228,T 1228,T Thesis


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