Single Nucleotide Polymorphisms In Pouifi Gene And Its Association With Milk Production Traits In Pakistani Cattle (Record no. 3086)
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| 000 -LEADER | |
|---|---|
| fixed length control field | 02215nam a2200193Ia 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20151005151022.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150525s2011 xx 000 0 und d |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 1373,T |
| 100 ## - MAIN ENTRY--AUTHOR NAME | |
| Personal name | Sadia Munir |
| 110 ## - MAIN ENTRY--CORPORATE NAME | |
| Location of meeting | Dr. Asif Nadeem |
| 245 ## - TITLE STATEMENT | |
| Title | Single Nucleotide Polymorphisms In Pouifi Gene And Its Association With Milk Production Traits In Pakistani Cattle |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Year of publication | 2011 |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | In farm animals, the primary focus of selection has been to improve milk yield. Milk field is a polygenic trait and a few potential candidate genes have been recognized. Association studies have shown that POUlFl is related to many production traits in domestic animals and is one of those candidate genes that are involved in milk production. POUl F 1 encodes a pituitary-specific transcription factor. It is well established that growth hormone (GH) released from pituitary gland plays an essential role in growth, mammary gland development and lactation process. The bovine POUlFl gene is of 15952 bp length having 6 exons. The genetic characterization of the POUlFl gene to identify the SNPs as genetic markers and validation of these potential markers by associating them with milk production traits has been performed. A total 35 samples from Sahiwal and 30 from Holstein-Friesian cattle breeds were sequenced for all 6 exonic portions of the POUlFl by using 6 sets of primers. A total 15 polymorphic sites in Sahiwal and 14 in Holstein-Friesian were identified from these sequences. Out of total 15 SNPs identified in Sahiwal, 12 were in intronic region and 3 were in exonic. Out of 14 SNPs identified in Holstein-Friesian, 10 were in intronic and 4 were in exonic region. The sequences of the amplified POUl F 1 gene fragments were aligned with the help of BLAST for SNPs identification. This study is first step in finding some confirmed markers for milk yield in Sahiwal and Holstein- Friesian cattle breed that can be used in future for selection and breeding programmes. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Institute of Biochemistry & Biotechnology |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dr. Abu Saeed |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dr. Muhammad Wasim |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Thesis |
| Damaged status | Collection code | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Accession Number | Koha item type |
|---|---|---|---|---|---|---|---|---|
| Veterinary Science | UVAS Library | UVAS Library | Thesis Section | 2015-05-29 | 1373,T | 1373,T | Thesis |