Prevalence And Therapeutic Studies On Diabetes Mellitus In Pet Dogs At Lahore. (Record no. 3173)
[ view plain ]
| 000 -LEADER | |
|---|---|
| fixed length control field | 04295nam a2200193Ia 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20151006130234.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 150525s2012 xx 000 0 und d |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 1467,T |
| 100 ## - MAIN ENTRY--AUTHOR NAME | |
| Personal name | Salman Khalid |
| 110 ## - MAIN ENTRY--CORPORATE NAME | |
| Location of meeting | Prof. Dr. Muhammad Sarwar Khan |
| 245 ## - TITLE STATEMENT | |
| Title | Prevalence And Therapeutic Studies On Diabetes Mellitus In Pet Dogs At Lahore. |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Year of publication | 2012 |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | Diabetes mellitus is one of the most important maladies of endocrine glands in dog and cats. It is due to the insufficient production of insulin by the pancreas. The multi-factors such as obesity, feeding, exposure to toxic drugs etc. are involved for the onset of this chronic disease. The basic energy fuel of the body is glucose. In the absence of insulin the glucose level in the blood is increases which can be noticed as hyperglycemia (high blood glucose level). There are the three types of diabetes mellitus which includes insulin-dependent diabetes mellitus (type I or IDDM), noninsulin-dependent diabetes mellitus (type II or NIDDM) and secondary diabetes mellitus. The dogs play a vital role in our society. The present study was conducted on diabetes mellitus to study its prevalence, its effect on various blood parameters and to evaluate the efficacy of insulin therapy in pet dogs in Lahore, Pakistan. The 500 blood samples were collected from the dogs of age ?5 years, presented at Pet centre of the University of Veterinary and Animal Sciences (UVAS) Lahore and various private clinics in Lahore, and was processed in Medicine Laboratory of UVAS, Lahore. The blood glucose level was measured with the aid of glucometer. Out of 500, 16 (n=5 male & n=11 females) were positive for diabetes mellitus. The 3.2% prevalence of diabetes mellitus was recorded in pet dogs in Lahore. The study concluded that the prevalence of diabetes mellitus in female dogs (68.75%) was significantly (p<0.05) higher than that of male dogs (31.25%). The results of this study showed that the prevalence of diabetes mellitus was higher in old age dogs (>9 years) as compared with other age groups. Diabetes mellitus was found to be more prevalent in winter season same as in human beings. The clinical signs like Polyuria (81.25%), Polydipsia (68.75%), Hyperglycemia (100%), Dehydration (43.75%), Anemia (56.25%) and cataract (18.75%) were commonly observed in diabetic dogs. In the present study the pet dog breed like Yorkshire terrier, Samoyed, Pomuranian and Cross bred were prone to have diabetes mellitus whereas German shepherd, Bull dogs, Pugs and Labrador retriever were at low risk for this malady. In the present project, the haematological study was conducted on 28 dogs (n=14 diabetic and n=14 healthy dogs). The five ml blood sample were collected from each dog directly from the cephalic vein and were shifted into a sterilized plastic bottle coated with EDTA@1mg/ml and were further analyzed through haemtological analyzer. The results showed the decreased number of RBCs (4.63±0.42) and an increased in PCV values (62.91±4.18). The results also showed dehydration and anemia in diabetic dogs. In the present study the 21 dogs (n= 14 diabetic dogs, n= 7 healthy dogs) were selected for therapeutic trials. The dogs were divided into further three groups; A, B and C. Each study group was comprised of 7 animals. Group A (comprised of diabetic dogs) was treated with Humulin-N (Insulin) @ 0.5 U/Kg, q12h, SC for 7 days. The group B (comprised of diabetic dogs) was kept as positive control while the healthy dogs were kept in group C for negative control. After the seven days treatment of group A, the blood samples were collected every 2 hr interval for 12 hrs for measuring the glucose value. The process was repeated once in a week for one month. The four blood glucose curves were made. Each blood glucose curve has its own nadir value. The time of glucose nadir value was indicated the peak action of insulin. The blood glucose curves were made to evaluate the effectiveness of insulin. The therapeutic results of this study concluded that the Humulin-N (insulin) was much effective for management of diabetic dogs. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Department of Clinical Medicine & Surgery |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dr. Muhammad Ijaz |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Prof. Dr. |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Thesis |
| Damaged status | Collection code | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Accession Number | Koha item type |
|---|---|---|---|---|---|---|---|---|
| Veterinary Science | UVAS Library | UVAS Library | Thesis Section | 2015-05-29 | 1467,T | 1467,T | Thesis |