Effect Of Vitis Vinifera (Grapes) Fruit Juice On Angiogenesis. (Record no. 3205)

000 -LEADER
fixed length control field 02194nam a2200193Ia 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20151006131357.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 150525s2012 xx 000 0 und d
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 1501,T
100 ## - MAIN ENTRY--AUTHOR NAME
Personal name Shahzad Asghar
110 ## - MAIN ENTRY--CORPORATE NAME
Location of meeting Prof. Dr. Muhammad Ashraf
245 ## - TITLE STATEMENT
Title Effect Of Vitis Vinifera (Grapes) Fruit Juice On Angiogenesis.
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Year of publication 2012
502 ## - DISSERTATION NOTE
Dissertation note Angiogenesis, the novel blood vessels formation, is a mark of nearly every neoplastic and non-neoplastic degenerative disease. Thetreatment of angiogenesis with plant derived anti-angiogenic substances may be proved as more efficacious,harmless, and lowbudget therapies. Grapes contain many vital natural compounds which can significantly prevent diseases and maintain human health. In this work, we have studied the effect of grapes juice (Vitis vinifera) on angiogenesis by use of chicken chorioallantoic membrane (CAM) assay. We took Fresh fertilized eggs and sprayed them with 70% ethanol for decontamination and incubated at 37?C and (humidity 65%-70%). At 5th day of incubation small windows were made on all eggs, 4-5 ml of albumin was extracted, windows were sealed with sterile Para-film tape and eggs were reincubated. Grapes juice was obtained from fully ripened grapes and various dilutions were formulated by using distilled water. Dilutions of the juice were filtered by special syringe filters used for experimental analysis and applied to the CAMs on 6th day of incubation. Changes in vessels were clearly observed macroscopically among all treated CAMs on 7th day of incubation. The total diameter & area of primary, secondary and tertiary blood vessels was observed to be reduced after treatment with grapes juice in a concentrationand dose related manner. Scanning probe image processor(SPIP)software was used for 3D surface roughness measurements which clearly demonstrated the antiangiogenic effect of grapes juice on CAM. Grapes (Vitis vinifera) juice inhibits angiogenesis, which is a common denominator of various major diseases.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term Department of Pharmaoclogy & Toxicology
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Dr. Muhammad Ovais Omer
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Prof. Dr.
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Thesis
Holdings
Damaged status Collection code Permanent Location Current Location Shelving location Date acquired Full call number Accession Number Koha item type
  Veterinary Science UVAS Library UVAS Library Thesis Section 2015-05-29 1501,T 1501,T Thesis


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