Effect Of Different Treatment Trials On The Carrier Status Of Streptococcus Equi In Horses Recently Recovered From Strangles (Record no. 6233)

000 -LEADER
fixed length control field 03855nam a22002177a 4500
005 - DATE AND TIME OF LATEST TRANSACTION
control field 20151008134353.0
008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION
fixed length control field 150921b2015 xxu||||| |||| 00| 0 eng d
041 ## - LANGUAGE CODE
Language code of text/sound track or separate title eng
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 2299-T
100 ## - MAIN ENTRY--AUTHOR NAME
Personal name Muhammad Afzal (2007-VA-108)
110 ## - MAIN ENTRY--CORPORATE NAME
Location of meeting Dr. Muhammad Hassan Saleem
245 ## - TITLE STATEMENT
Title Effect Of Different Treatment Trials On The Carrier Status Of Streptococcus Equi In Horses Recently Recovered From Strangles
260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT)
Year of publication 2015
300 ## - PHYSICAL DESCRIPTION
Number of Pages 52p.;
502 ## - DISSERTATION NOTE
Dissertation note Strangles is characterized by upper respiratory tract infection, dysponea, anorexia, regional suppurative lymphadenitis causing high morbidity and low mortality in horses as well as in mules and it is an infectious problem of equine. Considering the significance and utilization of equines in our country and the substantial losses rendered by Strangles, the present project was designed to study epidemiology, diagnosis and chemotherapy of strangles in Lahore, Okara and Sargodha districts of the Punjab province in Pakistan. Streptococcus equi subspecies equi is highly prevalent in animals recently recovered from strangles and antibiotics along with immune stimulants and non steroidal anti-inflammatory drug became helpful in the elimination of carrier status of animals for S. equi. Samples were collected from animals recently recovered from Strangles. Samples were collected with the help of sterile cotton swabs dipped in normal saline from nasopharynx & oropharynx followed by culturing of samples on blood agar plates which were incubated anaerobically for a time period of 24-48 hours respectively and S. equi were isolated on the basis of colonies characteristics and growth pattern. Streptococcus equi was confirmed with the help of Gram staining and biochemical tests Catalase reaction, Methylene blue reduction test and Sugar fermentation test. In vitro antibiotic sensitivity test were also performed to select three antibiotics showing best efficacy against S. equi. Carrier animals were subjected to treatment with the help of antibiotic along with combination of immune stimulants and non steroidal anti-inflammatory drug. Carrier status was considered eliminated with disappearance of S. equi from nasopharynx. Blood samples were collected from carrier as well as from healthy animals to check out hematological parameters such as TLC (total leukocytes count), TEC (total erythrocytes count) and MHC (mean hemoglobin concentration) etc. Out of
Summary
47
hundred samples collected from Sargodha, Lahore and Okara districts of Punjab the prevalence of S. equi in horses and mules was 15%. Highest prevalence in equines was found at Remount Depot Mona, was recorded which is 18.3% followed by Okara 13.33%. No case was found to be positive for Strangles out of ten samples collected at UVAS, Lahore.
In-vitro antibiotic sensitivity test was performed on above isolates and it was found that ceftiofur Na was found to be most effective drug followed by norfloxacine and ampicillin. In vivo treatment trials showed that Group C animals treated with ceftiofur Na, norfloxacine, and ampicillin along with Vit E & Selenium supplemented by Phenyl butazone were found to be negative for post treatment carrier status. This study had aided in diagnosis as well as in treatment of strangles and was also provided us with the understanding of hematological parameters.
Statistical analysis:
 Data on prevalence of S. equi in carrier animals were analyzed by Chi square test.
 While comparison of different treatments trials was done by Z test.
 Hematological parameters were analyzed by mean ± SED using SPSS software 16.0.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term Department of Clinical Medicine and Surgery
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical Term Clinical Medicine
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Prof. Dr. Aneela Zameer Durrani
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Dr. Hassaan Bin Aslam
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Koha item type Thesis
Holdings
Damaged status Collection code Permanent Location Current Location Shelving location Date acquired Full call number Accession Number Koha item type
  Veterinary Science UVAS Library UVAS Library Thesis Section 2015-09-21 2299-T 2299-T Thesis


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