Characterization And Phylogenetic Analysis Of Neuraminidase Gene Of Avian Influenza Virus Subtype H9N2 (Record no. 8676)
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| fixed length control field | 02335nam a22002057a 4500 |
| 005 - DATE AND TIME OF LATEST TRANSACTION | |
| control field | 20160711093717.0 |
| 008 - FIXED-LENGTH DATA ELEMENTS--GENERAL INFORMATION | |
| fixed length control field | 160711b2016 xxu||||| |||| 00| 0 eng d |
| 041 ## - LANGUAGE CODE | |
| Language code of text/sound track or separate title | eng |
| 082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER | |
| Classification number | 2458-T |
| 100 ## - MAIN ENTRY--AUTHOR NAME | |
| Personal name | Muhammad Abid (2014-VA-502) |
| 110 ## - MAIN ENTRY--CORPORATE NAME | |
| Location of meeting | Prof. Dr. Tahir Yaqub |
| 245 ## - TITLE STATEMENT | |
| Title | Characterization And Phylogenetic Analysis Of Neuraminidase Gene Of Avian Influenza Virus Subtype H9N2 |
| 260 ## - PUBLICATION, DISTRIBUTION, ETC. (IMPRINT) | |
| Year of publication | 2016. |
| 300 ## - PHYSICAL DESCRIPTION | |
| Number of Pages | 51p.; |
| 502 ## - DISSERTATION NOTE | |
| Dissertation note | The H9N2 AIV are endemic in Pakistan since 1998 and causing serious outbreaks in poultry industry leading to increased morbidity and mortality, reduced egg production and reduced weight gain thus causing great economic losses. As these viruses have segmented genome so there is a lots of antigenic shift, antigenic drift and genetic reassortment which results in the production of new AIV subtypes. Besides causing significant losses the poultry industry, the H9N2 AIV pose a significant threat to public health and this issue has been pronounced with the fact that these viruses caused infections in Chinese children in 1999. This primary focus of this study was to characterize and to determine the phylogenetic relationship of the N2 gene of H9N2 AIV prevalent in Pakistan with other H9N2 viruses. A total of 10 H9N2 AIV were isolated from 100 samples and analyzed through serological and molecular tests. N2 gene of three isolates was amplified and sequenced. The isolates showed 99% homology with the H9N2 AIV recently isolated from Pakistan and their phylogenetic analysis revealed that all belonged to the same G-1 lineage and fell in clusters of more recently and closely related H9N2 viruses. There were some amino acid substitutions in different positions of the NA gene as compared to previous H9N2 viruses of Pakistan and these substitutions were the same to other H9N2 viruses isolated in 2015 from Pakistan. Due to the mutating nature of the H9N2 AIV there is need for the continuous surveillance and characterization of the prevailing H9N2 avian influenza viruses as these virus have the potential to cause serious outbreaks in poultry and also pose a significant threat to the public health. |
| 650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM | |
| Topical Term | Department of Microbiology |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Dr. M. Zubair Shabbir |
| 700 ## - ADDED ENTRY--PERSONAL NAME | |
| Personal name | Prof. Dr. Aneela Zameer Durrani |
| 942 ## - ADDED ENTRY ELEMENTS (KOHA) | |
| Koha item type | Thesis |
| Damaged status | Collection code | Permanent Location | Current Location | Shelving location | Date acquired | Full call number | Accession Number | Koha item type |
|---|---|---|---|---|---|---|---|---|
| Veterinary Science | UVAS Library | UVAS Library | Thesis Section | 2016-07-11 | 2458-T | 2458-T | Thesis |