Normal view MARC view ISBD view

Comparative Hematology And Histopathology Of Parvo Virus And Corona Virus Infections In Dogs

By: Qazi Abdul Aziz (2012-VA-984) | Mr. Irfan Irshad.
Contributor(s): Prof. Dr. Asim Aslam | Prof. Dr. Habibur Rehman.
Material type: materialTypeLabelBookPublisher: 2016Description: 47p.Subject(s): PathologyDDC classification: 2641-T Dissertation note: Canine viral enteritis is a disease of dogs with an acute onset of vomiting and diarrhea, especially in puppies. Four viruses have been identified as the essential cause of severe enteritis in dogs: Canine Parvo Virus (CPV), Canine Corona Virus (CCV), Canine Rota Virus and Canine Distemper Virus (Jones et al. 1997; Buonavoglia et al. 2006). CPV is a contagious viral disease of dogs and is one of the most important causes of deaths in puppies (Decaro et al. 2005). Puppies aged between six and twenty weeks old, are most susceptible to CPV. CCV was first isolated in 1971 from gastro enteric dogs. Subsequently additional cases have been reported that were usually mild and self-limiting, unless complicated by CPV (Jones et al. 1997). CCV is mainly associated with respiratory, enteric, hepatic and central nervous system diseases. Nevertheless, organs such as kidney, heart, and eye can also be affected. Infections are usually self-limiting but may fatal in young animals (Pratelli et al. 2004; Evermann et al. 2005).Canine coronavirus (CCV) and canine parvovirus (CPV) are pathogens responsible for acute gastroenteritis in dogs (Decaro et al. 2008; Holzer and Parrish 2010). Canine coronavirus infection was regarded as a mild, self-limiting infection of the small intestine, especially in puppies (Decaro et al. 2008). CPV and CCV are immensely infectious viral diseases of dogsof all ages but young pups are mostly affected. Vulnerability of infection depends on age and immune status of animals. Infection is more severe in young dogs.A total of fifty clinically positive animals were selected with strong clue of gastro enteritis at various pet clinics in district Lahore. Gross pathological examinations of animals were done prior to sampling.Anorexia, emaciation, vomition, foul-smelling bloody diarrhea, temperature, depression, rough coat, and color of mucous membranes were gross pathological finding in positive animals. Less than six months ages of dogs were more affected as compared to dogs above from this age. Similarly small pupswere more challenging. Histopathology and hematology was done for positive animals. Hematological examination was statistically analyzed with one way ANOVA with the help of SAS version 9.1. Results were statistically significant and there was decrease in WBCs, Lymphocytes count and platelets count. Histopathological studies revealed the degeneration of intestinal epithelium, infiltration of mononuclear cells principally macrophages and neutrophils and blood vessels were filled with RBCs. Objectives of current study was to characterize the clinical, hematological and histopathological findings in dogs diagnosed with CCV and CPV natural infections in order to explore their usefulness as laboratory markers for the differential diagnosis of CPV and CCV.
Tags from this library: No tags from this library for this title. Add tag(s)
Log in to add tags.
    average rating: 0.0 (0 votes)

Canine viral enteritis is a disease of dogs with an acute onset of vomiting and diarrhea, especially in puppies. Four viruses have been identified as the essential cause of severe enteritis in dogs: Canine Parvo Virus (CPV), Canine Corona Virus (CCV), Canine Rota Virus and Canine Distemper Virus (Jones et al. 1997; Buonavoglia et al. 2006). CPV is a contagious viral disease of dogs and is one of the most important causes of deaths in puppies (Decaro et al. 2005). Puppies aged between six and twenty weeks old, are most susceptible to CPV. CCV was first isolated in 1971 from gastro enteric dogs. Subsequently additional cases have been reported that were usually mild and self-limiting, unless complicated by CPV (Jones et al. 1997). CCV is mainly associated with respiratory, enteric, hepatic and central nervous system diseases. Nevertheless, organs such as kidney, heart, and eye can also be affected. Infections are usually self-limiting but may fatal in young animals (Pratelli et al. 2004; Evermann et al. 2005).Canine coronavirus (CCV) and canine parvovirus (CPV) are pathogens responsible for acute gastroenteritis in dogs (Decaro et al. 2008; Holzer and Parrish 2010). Canine coronavirus infection was regarded as a mild, self-limiting infection of the small intestine, especially in puppies (Decaro et al. 2008).
CPV and CCV are immensely infectious viral diseases of dogsof all ages but young pups are mostly affected. Vulnerability of infection depends on age and immune status of animals. Infection is more severe in young dogs.A total of fifty clinically positive animals were selected with strong clue of gastro enteritis at various pet clinics in district Lahore. Gross pathological examinations of animals were done prior to sampling.Anorexia, emaciation, vomition, foul-smelling bloody diarrhea, temperature, depression, rough coat, and color of mucous membranes were gross pathological finding in positive animals. Less than six months ages of dogs were more affected as compared to dogs above from this age. Similarly small pupswere more challenging. Histopathology and hematology was done for positive animals. Hematological examination was statistically analyzed with one way ANOVA with the help of SAS version 9.1. Results were statistically significant and there was decrease in WBCs, Lymphocytes count and platelets count. Histopathological studies revealed the degeneration of intestinal epithelium, infiltration of mononuclear cells principally macrophages and neutrophils and blood vessels were filled with RBCs. Objectives of current study was to characterize the clinical, hematological and histopathological findings in dogs diagnosed with CCV and CPV natural infections in order to explore their usefulness as laboratory markers for the differential diagnosis of CPV and CCV.

There are no comments for this item.

Log in to your account to post a comment.


Implemented and Maintained by UVAS Library.
For any Suggestions/Query Contact to library or Email:rehana.kousar@uvas.edu.pk Phone:+91 99239068
Website/OPAC best viewed in Mozilla Browser in 1366X768 Resolution.