Studies On Histopathology Of Brain And Salivary Glands Of Dogs Suspected For Rabies
By: Shakil Akhtar Khan
| Tufail Muhammed Khan.
Contributor(s): Ata-Ur-Rehman | Manzoor Ahmed Basra | Faculty of Veterinary Sciences.
Material type: 
BookPublisher: 1986Subject(s): Department of PathologyDDC classification: 0262,T Dissertation note: Rabies is a fatal viral disease of all warm blooded animals, including man. Because of its highly fatal nature it is the most notorious and dreaded disease in dogs. The disease in man is characterized by an emotional and neurological disorders with relfex excitability, paralysis and death. The infectious agent of rabies is a neurotropic member of the family Rhabdoviridae found in the nerve tissue, tears, saliva, salivary glands and rarely in other body fluids.
A total of thirty stray dogs and thirty dogs suspected for rabies were included in the present work. From the both groups, the impression smear5were prepared (of hippocampus, cerebellum and mandibular salivary gland) for detection of Negri bodies. Biological test in mice and histopathological changes of bippocampus, cerebellum and mandibular salivary glauds were noted. Out of 30 stray dogs the impression smears of three hippocampus and one cerebellum were doubtful for Negri bodies and all the mandibular salivary glands were negative, for Negri bodies. The biological test in mice was negative for rabies in all stray dogs. The impression smears from thirty dogs suspected for rabies, showed Negri bodies in twelve hippocampus, seven cerebellum and all the mandibular salivary glands were found negative for Negri bodies. Seventeen dogs out of 30 dogs were biological positive for rabies. Histopathological changes were observed in fourteen hippocampus, fourteen cerebellum and ten mandibular salivary glands.
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Thesis
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UVAS Library Thesis Section | Veterinary Science | 0262,T (Browse shelf) | Available | 0262,T |
Rabies is a fatal viral disease of all warm blooded animals, including man. Because of its highly fatal nature it is the most notorious and dreaded disease in dogs. The disease in man is characterized by an emotional and neurological disorders with relfex excitability, paralysis and death. The infectious agent of rabies is a neurotropic member of the family Rhabdoviridae found in the nerve tissue, tears, saliva, salivary glands and rarely in other body fluids.
A total of thirty stray dogs and thirty dogs suspected for rabies were included in the present work. From the both groups, the impression smear5were prepared (of hippocampus, cerebellum and mandibular salivary gland) for detection of Negri bodies. Biological test in mice and histopathological changes of bippocampus, cerebellum and mandibular salivary glauds were noted. Out of 30 stray dogs the impression smears of three hippocampus and one cerebellum were doubtful for Negri bodies and all the mandibular salivary glands were negative, for Negri bodies. The biological test in mice was negative for rabies in all stray dogs. The impression smears from thirty dogs suspected for rabies, showed Negri bodies in twelve hippocampus, seven cerebellum and all the mandibular salivary glands were found negative for Negri bodies. Seventeen dogs out of 30 dogs were biological positive for rabies. Histopathological changes were observed in fourteen hippocampus, fourteen cerebellum and ten mandibular salivary glands.
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