A Study Of Blood Parameters And Comparative Efficacy Of Different Fasciolicidal Drugs Against Faiscioliasis
By: Atif Nazir haji
| Khalid Pervaiz.
Contributor(s): Mubasher | Muhammed Sarwer Khan | Faculty of Veterinary Sciences.
Material type: 
BookPublisher: 1993Subject(s): Department of Clinical Medicine & SurgeryDDC classification: 0303,T Dissertation note: A study was conducted to find out the haematological changes, total serum protein and relative efficacy of three drugs i.e. Fasinex (Ciba Giegy), Trodax (May & Baker) and Valbazen (S.K&B) against fascioliasis in naturally infected goats. The study was made from zero to 21st days in October-November, 1992.
Flaematological changes were observed after examining the total erythrocyte count, total leukocyte count, differential leucocyte count, packed cell volume, haemoglobin estimation and total serum protein of 40 naturally infected goats in Gujranwala district. It was concluded that there was,a drop in erythrocyte count, packed cell volume and haemoglobin concentration in the infected goats and a normocytic normochrornic type of anemia was detected. The study of differential leucocyte count revealed that there was marked eosinophilia with slight decrease in neutrophils and slight increase in lymphocyte count in the infected goats. Besides this, it was also noticed and recorded that there was also decrease in the total serum protein level of the same 40 infected goats which were naturally infected with fascioliasis. These goats were divided into four groups 'A', '13', 'C' and 'D' of 10 animals each for the study of the efficacy of three antifascioliatic drugs (Fasinex, Trodax, and Valbazen) at manufacturer's recommended dose rates after wards. Three groups (A, B & C) was given a separate drug on the zero day and the fourth group (D Group) was left untreated as a control. The efficacies recorded were 94.59% and 81.08% and 80.55 for Fasinex, Trodax and Valbazen respectively.
The data were analysed statistically by applying the statistical technique two factors Randomized complete Block Design and least significant difference test.
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Thesis
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UVAS Library Thesis Section | Veterinary Science | 0303,T (Browse shelf) | Available | 0303,T |
A study was conducted to find out the haematological changes, total serum protein and relative efficacy of three drugs i.e. Fasinex (Ciba Giegy), Trodax (May & Baker) and Valbazen (S.K&B) against fascioliasis in naturally infected goats. The study was made from zero to 21st days in October-November, 1992.
Flaematological changes were observed after examining the total erythrocyte count, total leukocyte count, differential leucocyte count, packed cell volume, haemoglobin estimation and total serum protein of 40 naturally infected goats in Gujranwala district. It was concluded that there was,a drop in erythrocyte count, packed cell volume and haemoglobin concentration in the infected goats and a normocytic normochrornic type of anemia was detected. The study of differential leucocyte count revealed that there was marked eosinophilia with slight decrease in neutrophils and slight increase in lymphocyte count in the infected goats. Besides this, it was also noticed and recorded that there was also decrease in the total serum protein level of the same 40 infected goats which were naturally infected with fascioliasis. These goats were divided into four groups 'A', '13', 'C' and 'D' of 10 animals each for the study of the efficacy of three antifascioliatic drugs (Fasinex, Trodax, and Valbazen) at manufacturer's recommended dose rates after wards. Three groups (A, B & C) was given a separate drug on the zero day and the fourth group (D Group) was left untreated as a control. The efficacies recorded were 94.59% and 81.08% and 80.55 for Fasinex, Trodax and Valbazen respectively.
The data were analysed statistically by applying the statistical technique two factors Randomized complete Block Design and least significant difference test.
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