Immunogenic Studies On Temperature Resistant V4 Strain Of Newcastle Disease Virus
By: Sakhawat Hussain, Shah
| Sheikh Muhammed Amin.
Contributor(s): Manzoor | Muhammed Akram Muneer | Faculty of Veterinary Sciences.
Material type: 
BookPublisher: 1993Subject(s): Department of MicrobiologyDDC classification: 0307,T Dissertation note: This experiment was conducted to study the immunogenic response of '14 strain of NOV which was administered through different routes normaly practiced in Pakistan (eyedrop, drinking water, subcut and intramuscular)
Birds in group A were vaccinated intraocularly on 7th day of age and then on 21st day of age they were again vaccinated subcutaneously with '14 strain of NOV . The GMT titer on 12nd day of their. age was 169 and they showed 757. survival when challenged with VVNDV.
Group B was administered V4 strain of NDV in drinking water twice on 7th day of age and on 21st day of age. Their GMT HI titre on 42nd day was 104 .They showed 70%. protection percentage when challenged with virulent virus.
Chicks of group C were vaccinated introcularly with V4 strain on 7th day of their age and intramuscularly on 21st day of their age with V4. Their sera when analysed on 42nd day of age indicated GMT HI titre of 181. They showed highest protection 807. when , Challenged with virulent virus.
Group 0 was vaccinated intraocularlywith Mukteswar strain of MDV on 7th day again substaneously on 2lth day . Their GMT H.I titre was 194 on 42nd day of age.
Challenged with VVNDV protected 85% birds.
This study indicates that V4 strain of NOV induces higher H I titer and protection percentage when administered 1/rn than S/C and drinking water routes. However Mukteswar strain gives more HI titer and protection than V4 strain through S/C route.
| Item type | Current location | Collection | Call number | Status | Date due | Barcode | Item holds |
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Thesis
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UVAS Library Thesis Section | Veterinary Science | 0307,T (Browse shelf) | Available | 0307,T |
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This experiment was conducted to study the immunogenic response of '14 strain of NOV which was administered through different routes normaly practiced in Pakistan (eyedrop, drinking water, subcut and intramuscular)
Birds in group A were vaccinated intraocularly on 7th day of age and then on 21st day of age they were again vaccinated subcutaneously with '14 strain of NOV . The GMT titer on 12nd day of their. age was 169 and they showed 757. survival when challenged with VVNDV.
Group B was administered V4 strain of NDV in drinking water twice on 7th day of age and on 21st day of age. Their GMT HI titre on 42nd day was 104 .They showed 70%. protection percentage when challenged with virulent virus.
Chicks of group C were vaccinated introcularly with V4 strain on 7th day of their age and intramuscularly on 21st day of their age with V4. Their sera when analysed on 42nd day of age indicated GMT HI titre of 181. They showed highest protection 807. when , Challenged with virulent virus.
Group 0 was vaccinated intraocularlywith Mukteswar strain of MDV on 7th day again substaneously on 2lth day . Their GMT H.I titre was 194 on 42nd day of age.
Challenged with VVNDV protected 85% birds.
This study indicates that V4 strain of NOV induces higher H I titer and protection percentage when administered 1/rn than S/C and drinking water routes. However Mukteswar strain gives more HI titer and protection than V4 strain through S/C route.
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