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Effect Of Vitamin E Deficiency And Excess On Immune System Of Broiler Chickens

By: Fauzia Kaukab Bashir | Dr. Shakil Akhtar Khan.
Contributor(s): Dr. Muhammad | Dr. Shahzada Khurram Ashraf | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 1994Subject(s): Department of PathologyDDC classification: 0388,T Dissertation note: This study was carried out to investigate whether different dietary levels of vitamin E (recommended, deficient and excess) had any detrimental or beneificial effect on body weight gain, lymphoid organs, haemalotogical values, humoral response to NDV-vacci nation, eel I ular response to tuberculin and phagocytic activity of neutrophils of broiler chickens. The study indicated that vitamin E supplementation 300 lU/Kg feed had beneficial effects on the weight gain of birds, weight of lymphoid organs such as bursa of fabricius, spleen, thymus and liver; feed intake and feed conversion ratio; serum antibody development against NDV vaccination; phagocytic index and delayed hypersensitivity index. Whereas, vitamin E deficiency adversely affects the body weight gain; weights of lymphoid organs such as bursa of fabricius, spleen, thymus and liver; feed intake and feed conversion ratio, serum antibody development NDV vaccination; Phagocytic index and delayed hypersensitivity index. No significant effect of vitamin E supplementation/deficiecy was noted on haematological values. From the results of this study it is concluded that vitamin E is not an immunosuppressive agent when used at recommended leavels or even in excess. Vitamin E deficient level in diet lowersthe immunocompetance of broiler chicken, whereas vitamin E excess level in diet improved immune responses and body weight gain.
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This study was carried out to investigate whether different dietary levels of vitamin E (recommended, deficient and excess) had any detrimental or beneificial effect on body weight gain, lymphoid organs, haemalotogical values, humoral response to NDV-vacci nation, eel I ular response to tuberculin and phagocytic activity of neutrophils of broiler chickens.

The study indicated that vitamin E supplementation 300 lU/Kg feed had beneficial effects on the weight gain of birds, weight of lymphoid organs such as bursa of fabricius, spleen, thymus and liver; feed intake and feed conversion ratio; serum antibody development against NDV vaccination; phagocytic index and delayed hypersensitivity index. Whereas, vitamin E deficiency adversely affects the body weight gain; weights of lymphoid organs such as bursa of fabricius, spleen, thymus and liver; feed intake and feed conversion ratio, serum antibody development NDV vaccination; Phagocytic index and delayed hypersensitivity index.

No significant effect of vitamin E supplementation/deficiecy was noted on haematological values.

From the results of this study it is concluded that vitamin E is not an immunosuppressive agent when used at recommended leavels or even in excess. Vitamin E deficient level in diet lowersthe immunocompetance of broiler chicken, whereas vitamin E excess level in diet improved immune responses and body weight gain.

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