Studies On Blood Chemistry And Histopathological Alteration Induced By Mycoplasma Gallisepticum In Broiler
By: Shahida Parveen | Dr. Shakil Akhtar Khan.
Contributor(s): Dr. Asif | Dr. Shahzada Khurram Ashraf | Faculty of Veterinary Sciences.
Material type: BookPublisher: 1994Subject(s): Department of PathologyDDC classification: 0396,T Dissertation note: For this project 120 one-day-old broiler chicks were divided into two equal groups i.e. A and B. The birds in group B were challenged with Mycoplasma gallisepticum at 7 days of age, whereas those in group A were dealt with as control birds. After 21 days of post infection serum samples were obtained from the diseased as well as control birds during slaughtering. Tissue samples from lungs, liver and trachea were collected and processed for histopathological examination. The postmortem findings revealed catarrhal exudate in the flares, sinuses, trachea, lungs and oedema of airsacs wall. The lungs were congested, dark in colour and inflammed. Liver showed fibri nopurulent perihepatitis, haemorrhages and congestion. Trachea was found to have a tenacious viscous cloudy exudate which was adherent to the tracheal wall. The histopathological sections showed oedema, haemorrhages, congestion, massive infiltration of monocytes and heterophils in the lungs. The liver showed evidence of necrosis, haemorrhages and infiltration of heterophils, lymphocytes in interlobular spaces around portal vessels. The trachea showed epithelial and submucosal infiltration with lymphocytes, hypertrophy of epithelial mucous glands' and some catarrhal exudate on the mucosal surface. Sloughing of mucosa with variable degree was noted. The data, obtained by the analysis of serum, statistically indicated that the concentration of serum uric acid, serum glutamic pyruvic transaminase, serum alkaline phosphatase and serum lactic dehydrogenase was increased significantly in infected birds.Item type | Current location | Collection | Call number | Status | Date due | Barcode | Item holds |
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Thesis | UVAS Library Thesis Section | Veterinary Science | 0396,T (Browse shelf) | Available | 0396,T |
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For this project 120 one-day-old broiler chicks were divided into two equal groups i.e. A and B. The birds in group B were challenged with Mycoplasma gallisepticum at 7 days of age, whereas those in group A were dealt with as control birds. After 21 days of post infection serum samples were obtained from the diseased as well as control birds during slaughtering. Tissue samples from lungs, liver and trachea were collected and processed for histopathological examination.
The postmortem findings revealed catarrhal exudate in the flares, sinuses, trachea, lungs and oedema of airsacs wall. The lungs were congested, dark in colour and inflammed. Liver showed fibri nopurulent perihepatitis, haemorrhages and congestion. Trachea was found to have a tenacious viscous cloudy exudate which was adherent to the tracheal wall.
The histopathological sections showed oedema, haemorrhages, congestion, massive infiltration of monocytes and heterophils in the lungs. The liver showed evidence of necrosis, haemorrhages and infiltration of heterophils, lymphocytes in interlobular spaces around portal vessels. The trachea showed epithelial and submucosal infiltration with lymphocytes, hypertrophy of epithelial mucous glands' and some catarrhal exudate on the mucosal surface. Sloughing of mucosa with variable degree was noted.
The data, obtained by the analysis of serum, statistically indicated that the concentration of serum uric acid, serum glutamic pyruvic transaminase, serum alkaline phosphatase and serum lactic dehydrogenase was increased significantly in infected birds.
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