Effect Of Vitamin A Deficiency And Excess On Immune System Of Broiler Chickens
By: Ahmad Raza
| Dr. Shakil Akhtar Khan.
Contributor(s): Dr. Haji Ahmad | Dr. Shahzada Khurram Ashraf | Faculty of Veterinary Sciences.
Material type: 
BookPublisher: 1994Subject(s): Department of PathologyDDC classification: 0398,T Dissertation note: This study was conducted to investigate the effect of different dietary levels of vitamin A (Excess, deficient and recommended) on body weight gain, lymphoid organs, haematological values, humoral response to NDV-vaccination, cellular response to tuberculin and phagocytic activity of neutrophils of broiler chickens.
The results of the study revealed that vitamin A supplementation at 20,000 1U/Kg feed had beneficial effects on the weight gains of birds; weight of lymphoid organs such as bursa of Fabricius, spleen, thymus and liver; serum antibody development against NDV vaccination; feed intake and feed conversion ratio; phagocytic index and delayed hypersensitivity index. Whereas, vitamin A deficiency had adverse effects on body weight gains; weight of lymphoid organs, serum antibody development agaist NDV vaccination, feed intake and feed conversion ratio, phagocytic index and hypersensitivity index.
No significant effect of vitamin A supplementationldeficiency was noted on haematological values.
From the results of this study it can be concluded that vitamin A is not an immunosuppressive agent when used at recommended level or even in excess (for short duration). Vitamin A deficient level in diet had detrimental effects on immune system in terms of lowered humoral and cellular responses and also decreaed phagocytic activity of neutrophils. Whereas, vitamin A supplementation at excess level improves cellular and humoral responses along with improved phagocy bic activity of neutrophils.
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Thesis
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UVAS Library Thesis Section | Veterinary Science | 0398,T (Browse shelf) | Available | 0398,T |
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This study was conducted to investigate the effect of different dietary levels of vitamin A (Excess, deficient and recommended) on body weight gain, lymphoid organs, haematological values, humoral response to NDV-vaccination, cellular response to tuberculin and phagocytic activity of neutrophils of broiler chickens.
The results of the study revealed that vitamin A supplementation at 20,000 1U/Kg feed had beneficial effects on the weight gains of birds; weight of lymphoid organs such as bursa of Fabricius, spleen, thymus and liver; serum antibody development against NDV vaccination; feed intake and feed conversion ratio; phagocytic index and delayed hypersensitivity index. Whereas, vitamin A deficiency had adverse effects on body weight gains; weight of lymphoid organs, serum antibody development agaist NDV vaccination, feed intake and feed conversion ratio, phagocytic index and hypersensitivity index.
No significant effect of vitamin A supplementationldeficiency was noted on haematological values.
From the results of this study it can be concluded that vitamin A is not an immunosuppressive agent when used at recommended level or even in excess (for short duration). Vitamin A deficient level in diet had detrimental effects on immune system in terms of lowered humoral and cellular responses and also decreaed phagocytic activity of neutrophils. Whereas, vitamin A supplementation at excess level improves cellular and humoral responses along with improved phagocy bic activity of neutrophils.
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