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Efficacy Of Triclabendazole And Oxyclozanide Against Fascioliasis In Buffaloes And Their Effect On Blood Parameters

By: Amer Aziz | Prof.Dr.Muhammad Ashraf.
Contributor(s): Dr.Haji Ahmed | Dr.Khalid Pervaiz | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 1996Subject(s): Department of Clinical Medicine & SurgeryDDC classification: 0434,T Dissertation note: A comparative study was made among Fasinex 5% (Triclabendazole 50 mg/mi, Ciba Giegy), Endex 19.5% (Triclabendao1e 120 mg/mi + Levainisole 75 mg/mi, Ciba-Geigy) and Zanil 3% (Oxyclozanide 30 mg/mi, ICI) against fascioliasis in buffaloes and their effect on blood parameters. Sixty naturally infected buffaloes were selected and divided into four equal groups i.e. A, B, C and D containing 15 animals each. Each animal of Group A was given Fasinex 5% (1 ml/4.2 kg), Group B was given Endex 19.5% (1 mi/la kg), Group C was given Zanil 3% (1 ml/2 kg), while group D was kept as control. The mean efficacy of Fasinex 5% and Endex 19.5%, was 100% while Zanil 3% was 92.5% on 28th day post medication. Haematological changes were observed after examining the Total erythrocytic count, Haemoglobin estimation, Packed cell volume, Total leukocytic count and Differential leukocytic count which showed that there was a significant lower values for red blood cells counts (RBC), Haernoglobin (fib) and packed cell volume (PCV) while higher values were obtained for eósinophil counts in infected buffaloes. The data were analyzed statistically by applying One way Analysis of Variance (Anova Table) technique and Least significant difference test.
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A comparative study was made among Fasinex 5% (Triclabendazole 50 mg/mi, Ciba Giegy), Endex 19.5% (Triclabendao1e 120 mg/mi + Levainisole 75 mg/mi, Ciba-Geigy) and Zanil 3% (Oxyclozanide 30 mg/mi, ICI) against fascioliasis in buffaloes and their effect on blood parameters.

Sixty naturally infected buffaloes were selected and divided into four equal groups i.e. A, B, C and D containing 15 animals each. Each animal of Group A was given Fasinex 5% (1 ml/4.2 kg), Group B was given Endex 19.5% (1 mi/la kg), Group C was given Zanil 3% (1 ml/2 kg), while group D was kept as control.
The mean efficacy of Fasinex 5% and Endex 19.5%, was 100% while Zanil 3% was 92.5% on 28th day post medication.

Haematological changes were observed after examining the Total erythrocytic count, Haemoglobin estimation, Packed cell volume, Total leukocytic count and Differential leukocytic count which showed that there was a significant lower values for red blood cells counts (RBC), Haernoglobin (fib) and packed cell volume (PCV) while higher values were obtained for eósinophil counts in infected buffaloes.

The data were analyzed statistically by applying One way Analysis of Variance (Anova Table) technique and Least significant difference test.

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