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Efficacy Of Various Chemotherapeutic Agents Against Experimentally Induced Avian Mycoplasmosis In Broiler Chicks

By: Naveed Ahmad Khan Niazi | Dr. Muhammad Athar Khan.
Contributor(s): Dr. Asif | Dr. Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 1994Subject(s): Department of Clinical Medicine & SurgeryDDC classification: 0469,T Dissertation note: A total number of 200 day old broiler chicks were procured to determine the drug efficacy of tiamulin, tylosin and oxytetracycline against jylycoplasma gallisepticum infection in-vivo. The organism prior to its use was verified on the basis of morphology, staining reaction, cultural characteristics and biochemical tests. These birds were divided into 5 groups each having 40 birds. The birds of all groups were infected experimentally except group A birds. On the appearance of symptoms of CRD, group C, D and E were treated with tiamulin, tylosin and oxytetracycline respectively at the recommended doses of manufacturers for three consecutive days. The birds of group B were kept as untreated control. The efficacy of each drug was based upon morbidity percentage, mortality percentage, case fatality, clinical symptoms, feed-intake and necropsy lesions on postmortem. The tiamulin proved superior over other two drugs as only one bird died unlike tylosin-treated group D which recorded 2.5% mortality. The oxytetracycline treated group E showed 7.5% mortality with the death of 2 birds. A total of 29 birds revealed no pathological lesion at necropsy in contrast to group E birds showing only 27 birds without necropsy lesions of CRD. The feed-intake was poorest in group E and was remained normal in both group C and D. After 144 hours post medication, the clearance of lesions were 96.6%, 90% and 76.6% for group C, D and E respectively.
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Veterinary Science 0469,T (Browse shelf) Available 0469,T
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A total number of 200 day old broiler chicks were procured to determine the drug efficacy of tiamulin, tylosin and oxytetracycline against jylycoplasma gallisepticum infection in-vivo. The organism prior to its use was verified on the basis of morphology, staining reaction, cultural characteristics and biochemical tests. These birds were divided into 5 groups each having 40 birds. The birds of all groups were infected experimentally except group A birds. On the appearance of symptoms of CRD, group C, D and E were treated with tiamulin, tylosin and oxytetracycline respectively at the recommended doses of manufacturers for three consecutive days. The birds of group B were kept as untreated control. The efficacy of each drug was based upon morbidity percentage, mortality percentage, case fatality, clinical symptoms, feed-intake and necropsy lesions on postmortem. The tiamulin proved superior over other two drugs as only one bird died unlike tylosin-treated group D which recorded 2.5% mortality.

The oxytetracycline treated group E showed 7.5% mortality with the death of 2 birds. A total of 29 birds revealed no pathological lesion at necropsy in contrast to group E birds showing only 27 birds without necropsy lesions of CRD. The feed-intake was poorest in group E and was remained normal in both group C and D. After 144 hours post medication, the clearance of lesions were 96.6%, 90% and 76.6% for group C, D and E respectively.

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