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Efficacy Of Three Different Drugs Against Ectoparasites In Naturally Infested Dogs And Their Effect On Blood Parameters

By: Sharoon Sabir | Prof.Dr.Muhammad Ashraf.
Contributor(s): Dr. Khalid Pervaiz | Dr. Mubsher | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 1996Subject(s): Department of Clinical Medicine & SurgeryDDC classification: 0508,T Dissertation note: The present study was designed to evaluate and compare different drugs in 40 naturally infested dogs (based on skin scrapping examination) taken from Dog Hospital, College of Veterinary Sciences, Lahore and different Pet Clinics. Ivomec, Neguvon and Sulphur Tar Oil were used in three groups while one was control group. Treatment in each group was repeated after 14 days. Blood parameters i.e. Hemoglobin Estimation (Hb), Packed Cell Volume (PCV), Total Erythrocytic Count (TEC) and Total Leucocytic Count (TLC) were estimated. Results of treatment were evaluated on 14 days and 21 days after the first treatment on basis of skin scrapping examination and improvement in clinical symptoms. Efficacy of ivermectin, trichiorophon and sulphur tar oil was 80%, 70% and 40% on 14th day after 1st treatment. Same results were observed one week after second treatment indicating no additional benefit.Based on these observations it was concluded that ivermectin (200 µg/kg, s/c) was safe to use and its efficacy was significantly higher than Neguvon and Sulphurate oil. Moreover a single injection is sufficient for mild cases of ectoparasites but in severe cases second injection may be repeated after 14 days interval.
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The present study was designed to evaluate and compare different drugs in 40 naturally infested dogs (based on skin scrapping examination) taken from Dog Hospital, College of Veterinary Sciences, Lahore and different Pet Clinics. Ivomec, Neguvon and Sulphur Tar Oil were used in three groups while one was control group. Treatment in each group was repeated after 14 days. Blood parameters i.e. Hemoglobin Estimation (Hb), Packed Cell Volume (PCV), Total Erythrocytic Count (TEC) and Total Leucocytic Count (TLC) were estimated. Results of treatment were evaluated on 14 days and 21 days after the first treatment on basis of skin scrapping examination and improvement in clinical symptoms.
Efficacy of ivermectin, trichiorophon and sulphur tar oil was 80%, 70% and 40% on 14th day after 1st treatment. Same results were observed one week after second treatment indicating no additional benefit.Based on these observations it was concluded that ivermectin (200 µg/kg, s/c) was safe to use and its efficacy was significantly higher than Neguvon and Sulphurate oil. Moreover a single injection is sufficient for mild cases of ectoparasites but in severe cases second injection may be repeated after 14 days interval.

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