Immunomodulatory Effects Of Chloramphenicol In Broiler Chicks
By: Zubair Ulass
| Dr. M. Akram Munir.
Contributor(s): Dr. M. Naeem | Dr. M. Sarwar Khan | Faculty of Veterinary Sciences.
Material type: 
BookPublisher: 1998Subject(s): Department of MicrobiologyDDC classification: 0556,T Dissertation note: The purpose of the present study was to evaluate effects of chioramphenicol on the inimune response of broiler chickens. The immuno-modulatory effects of chioramphenicol in chicks was evaluated using the following parameters:
a) Morphometric effects of chioramphenicol on immune organs such as Li ursa of Fabricius, Tliymus and Spleen.
b) Effects of cliloramphenicol on the development of antibody titres against Newcastle virus vaccine.
c) Potential of chioramphenicol treated and NDV vaccinated birds to resist virulent NDV challenge.
d) Comparison of body weight gains of chioramphenicol a iid treated and untreated birds.
The untreated control birds had higher mean body weight than chioramphenicol and cyclophosphamide treated birds.
Chioramphenicol treatment adversely affect the weight of bursa of Fabricius , spleen and thymus of birds. The normal dose of chioramphenicol slightly depressed the weight of immune organ than double dosage of chioramphenicol. Cycloposphamide treatment of birds in early life resulted in bursal atrophy and slight depression of splenic weight. The sera of untreated control vaccinated birds had higher antibody titres than chioramphenicol and cyclophospliatnide treated birds. The sera of chioramphenicol treated NDV vaccinated birds had lower antibdoy titres as compared to untreated control birds. The NDV vaccinated choramphenicol treated and NDV vaccinated cyelophosphamide treated birds had high post Nl)V challenge mortality than untreated control NDV vaccinated birds.
| Item type | Current location | Collection | Call number | Status | Date due | Barcode | Item holds |
|---|---|---|---|---|---|---|---|
Thesis
|
UVAS Library Thesis Section | Veterinary Science | 0556,T (Browse shelf) | Available | 0556,T |
The purpose of the present study was to evaluate effects of chioramphenicol on the inimune response of broiler chickens. The immuno-modulatory effects of chioramphenicol in chicks was evaluated using the following parameters:
a) Morphometric effects of chioramphenicol on immune organs such as Li ursa of Fabricius, Tliymus and Spleen.
b) Effects of cliloramphenicol on the development of antibody titres against Newcastle virus vaccine.
c) Potential of chioramphenicol treated and NDV vaccinated birds to resist virulent NDV challenge.
d) Comparison of body weight gains of chioramphenicol a iid treated and untreated birds.
The untreated control birds had higher mean body weight than chioramphenicol and cyclophosphamide treated birds.
Chioramphenicol treatment adversely affect the weight of bursa of Fabricius , spleen and thymus of birds. The normal dose of chioramphenicol slightly depressed the weight of immune organ than double dosage of chioramphenicol. Cycloposphamide treatment of birds in early life resulted in bursal atrophy and slight depression of splenic weight. The sera of untreated control vaccinated birds had higher antibody titres than chioramphenicol and cyclophospliatnide treated birds. The sera of chioramphenicol treated NDV vaccinated birds had lower antibdoy titres as compared to untreated control birds. The NDV vaccinated choramphenicol treated and NDV vaccinated cyelophosphamide treated birds had high post Nl)V challenge mortality than untreated control NDV vaccinated birds.
There are no comments for this item.