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Comparative Efficacy Of Buparvaquone And Oxytetracycline Against Theileriosis In Cattle And Their Effect On Blood

By: Sarvat Yab Khan | Prof.Dr.Muhammad Ashraf.
Contributor(s): Dr.Haji Ahmad | Dr.Muhammad Sarwar Khan | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 1998Subject(s): Department of Clinical Medicine & SurgeryDDC classification: 0558,T Dissertation note: Theileriosis is a serious disease of the cattle which is caused by species of Theileria resulting in death due to severe anaemia. The present study was conducted to evaluate the comparative efficacy of buparvaquone (Butalex, ICI) and oxytetracycline (Terramycin 100 PVP) and their effect on various blood parameters, viz, total erythrocytic count (TEC), total leukocytic count (TLC), packed cell volume (PCV) and haemoglobin estimation (Hb) in and around Lahore. Thirty infected cattle showing clinical signs of Theileriosis (diagnosed based on blood smear examination) were used in this study. These animals were randomly divided into 3 groups designated as A, B and C comprising 10 animals each. Besides this 10 healthy cattle were kept as control as group D. Haernatological examination revealed a significant decrease in the erythrocyte count, packed cell volume and haemoglobin level of the infected cattles. Total leukocyte count was also decreased. Animal of group A was treated with single intramuscular injection of Butalex at the dose rate of 2.5 mg/kg body weight. The efficacy of the drug was 90 per cent. There was marked increased in the erythrocyte, leukocyte, packed cell volume and haemoglobin concentration. Group B was treated with intramuscular injection of Terramycin 100 PVP at the dose rate of 10 mg/kg body weight. The efficacy of the drug was 40% and there was slight increase in the haematological values. riThe haematological values of group C were much more decreased while in group D, these values were just same. From this study, it is concluded that buparvaquone 2.5 mg/kg body weight (Butalex ICI) is the drug of choice for the treatment of Theileriosis under field condition in our country.
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Veterinary Science 0558,T (Browse shelf) Available 0558,T
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Theileriosis is a serious disease of the cattle which is caused by species of Theileria resulting in death due to severe anaemia. The present study was conducted to evaluate the comparative efficacy of buparvaquone (Butalex, ICI) and oxytetracycline (Terramycin 100 PVP) and their effect on various blood parameters, viz, total erythrocytic count (TEC), total leukocytic count (TLC), packed cell volume (PCV) and haemoglobin estimation (Hb) in and around Lahore.

Thirty infected cattle showing clinical signs of Theileriosis (diagnosed based on blood smear examination) were used in this study. These animals were randomly divided into 3 groups designated as A, B and C comprising 10 animals each. Besides this 10 healthy cattle were kept as control as group D.

Haernatological examination revealed a significant decrease in the erythrocyte count, packed cell volume and haemoglobin level of the infected cattles. Total leukocyte count was also decreased. Animal of group A was treated with single intramuscular injection of Butalex at the dose rate of 2.5 mg/kg body weight. The efficacy of the drug was 90 per cent. There was marked increased in the erythrocyte, leukocyte, packed cell volume and haemoglobin concentration.

Group B was treated with intramuscular injection of Terramycin 100 PVP at the dose rate of 10 mg/kg body weight. The efficacy of the drug was 40% and there was slight increase in the haematological values. riThe haematological values of group C were much more decreased while in group D, these values were just same.

From this study, it is concluded that buparvaquone 2.5 mg/kg body weight (Butalex ICI) is the drug of choice for the treatment of Theileriosis under field condition in our country.

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