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Comparative Efficacy Of Melia Azadarch Linn (Neem) And Sulphaquinoxaline Sodium Against Coccidiosis And Their Effect On Haemoglobin And Total Serum Protein In Rabbits

By: Wajid Mehmood | Muhammad Sarwar Khan, 15n (CMS).
Contributor(s): Muhammad Ashraf, 64 (CMS) | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 1999Subject(s): Department of Clinical Medicine & SurgeryDDC classification: 0644,T Dissertation note: Forty coccidia free rabbits reared at College of Veterinary Sciences, Lahore were divided into 4 groups A, B, C and D. Each comprising 10 rabbits. Groups A, B and C were inoculated with 50,000 oocyst/ml/animal orally and group D was kept as control. Groups A and B were treated with Melia azadarch Linn (Neem) at the dose rate of 200 mg/kg body weight in drinking water and suiphaquinoxaline sodium at the dose rate of 1 g/l in drinking for 5 days, respectively. Main clinical signs were anorexia, emaciation, Greenish or brownish diarrhoed, sitting hunched up with its legs extended forward and postmortem lesion like Haemorrhagic gastroenteritis, perimeal region is smeared with faecal material. Caecum and colon contained dark greenish or brownish faecal material. Morbidity rate in group A, B and C was observed on day 10th, i.e. 37.5%, 10% and 100% and mortality rate was 20%, Nil and 50%, respectively. No mortality and morbidity was observed in group D. OPG (Oocyst per gram) in group A, B and C on zero day was 57,000, 55,000 and 60,500 and on 7th day was 30200, 2000 and 81500 and on 10th day 11,500, Nil and 95,000, respectively. OPG significant decrease in group B than A. Haemoglobin estimation value and total serum protein in group A, B and C on zero day were 11.30 gIdl, 11.20 g/dl and 11.40 g/dl and 4.5 g/dl, 4.7, 4.6 gfdl, respectively. On 7th day Hb value 11.50, 12.00 and 10.80 g/dl. Total serum protein values 4.7, .2 and 4.1 g/dl on 10th day Hb values 12.00, 13.50 and 10.00 g/dl, respectively and total serum protein was 5.5, 6.3 and 3.9 g/dl, respectively. Further decrease in group C was observed during the experiment. A considerable increase in lib and total serum protein values of group B was observed than group A. So suiphaquinoxaline sodium proved better anticoccidial drug than Melia azadarch linn (Neem).
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Veterinary Science 0644,T (Browse shelf) Available 0644,T
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Forty coccidia free rabbits reared at College of Veterinary Sciences, Lahore were divided into 4 groups A, B, C and D. Each comprising 10 rabbits. Groups A, B and C were inoculated with 50,000 oocyst/ml/animal orally and group D was kept as control. Groups A and B were treated with Melia azadarch Linn (Neem) at the dose rate of 200 mg/kg body weight in drinking water and suiphaquinoxaline sodium at the dose rate of 1 g/l in drinking for 5 days, respectively. Main clinical signs were anorexia, emaciation, Greenish or brownish diarrhoed, sitting hunched up with its legs extended forward and postmortem lesion like Haemorrhagic gastroenteritis, perimeal region is smeared with faecal material. Caecum and colon contained dark greenish or brownish faecal material.
Morbidity rate in group A, B and C was observed on day 10th, i.e. 37.5%, 10% and 100% and mortality rate was 20%, Nil and 50%, respectively. No mortality and morbidity was observed in group D. OPG (Oocyst per gram) in group A, B and C on zero day was 57,000, 55,000 and 60,500 and on 7th day was 30200, 2000 and 81500 and on
10th day 11,500, Nil and 95,000, respectively. OPG significant decrease in group B than A.
Haemoglobin estimation value and total serum protein in group A, B and C on zero day were 11.30 gIdl, 11.20 g/dl and 11.40 g/dl and 4.5 g/dl, 4.7, 4.6 gfdl, respectively. On 7th day Hb value 11.50, 12.00 and 10.80 g/dl. Total serum protein values 4.7, .2 and
4.1 g/dl on 10th day Hb values 12.00, 13.50 and 10.00 g/dl, respectively and total serum protein was 5.5, 6.3 and 3.9 g/dl, respectively. Further decrease in group C was observed during the experiment. A considerable increase in lib and total serum protein values of group B was observed than group A.
So suiphaquinoxaline sodium proved better anticoccidial drug than Melia azadarch linn (Neem).

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