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Comparative Anthelmintic Efficacy Of Moxidectin, Ivermectin And Albendazole Against G.I.T. Nematodes Of Sheep Under Field Conditions

By: Ali Abdullah Shah, M | Prof.Dr.Muhammad Ashraf.
Contributor(s): Haji Ahmad | Muhammad Athar Khan | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 2000Subject(s): Department of Clinical Medicine & SurgeryDDC classification: 0649,T Dissertation note: In this experiment comparative anthelmentic efficacy of moxidectin, ivermectin and albendazole was studied in sheep under field conditions. For this purpose, 60 sheep positive for nematodal infestation and 20 negative based on faecal examination were selected from the field. They were divided into 4 groups A, B, C & D having 20 animals in each group. Animals of group-A, B, C were medicated with moxidectin (0.2 mg I kg SIC injection), ivermectin (0.2 mg / kg S/C injection) and albendazole (5 mg / kg, orally) respectively. Animals of group-D were kept as control group. Eggs per gram of faeces were counted by McMaster technique on day 0, 7th 141h day post medication. To calculate the weight gain by these animals, weight was measured on day 0, 28th day of post medication Based on the reduction in the number of eggs per gram of faeces, efficacy of moxidectin was estimated to be 98.65% and 99.7% on day 7 and day 14 post medication respectively. Efficacy of ivermectin was estimated to be 98.9% and 100% while that of albendazole 94.96% and 97.67% on day 7, day 14 respectively. The weight gain observed after 281h day of post medication was 1.18 kg, 1.37 kg, 1.05 kg, 0.5 kg for animals treated with moxidectin, ivermectin, albendazole and control groups respectively. In conclusion, moxidectin and ivermectin are injectable preparations available in the market and can be used for the treatment of nematodes in sheep under field conditions in this area quite successfully.
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Veterinary Science 0649,T (Browse shelf) Available 0649,T
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In this experiment comparative anthelmentic efficacy of moxidectin, ivermectin and albendazole was studied in sheep under field conditions. For this purpose, 60 sheep positive for nematodal infestation and 20 negative based on faecal examination were selected from the field. They were divided into 4 groups A, B, C & D having 20 animals in each group. Animals of group-A, B, C were medicated with moxidectin (0.2 mg I kg SIC injection), ivermectin (0.2 mg / kg S/C injection) and albendazole (5 mg / kg, orally) respectively. Animals of group-D were kept as control group. Eggs per gram of faeces were counted by McMaster technique on day 0, 7th 141h day post medication. To calculate the weight gain by these animals, weight was measured on day 0, 28th day of post medication

Based on the reduction in the number of eggs per gram of faeces, efficacy of moxidectin was estimated to be 98.65% and 99.7% on day 7 and day 14 post medication respectively. Efficacy of ivermectin was estimated to be 98.9% and 100% while that of albendazole 94.96% and 97.67% on day 7, day 14 respectively. The weight gain observed after 281h day of post medication was 1.18 kg, 1.37 kg, 1.05 kg, 0.5 kg for animals treated with moxidectin, ivermectin, albendazole and control groups respectively.

In conclusion, moxidectin and ivermectin are injectable preparations available in the market and can be used for the treatment of nematodes in sheep under field conditions in this area quite successfully.

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