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Effects Of Supplementation Of Selenium And Zing Alone And In Combination On The Immune Response Of Broiler Chicks

By: Ashfaq Ahmad | Dr. Asim Aslam.
Contributor(s): Dr. Shakil Akhtar Khan | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 2002Subject(s): Department of PathologyDDC classification: 0759,T Dissertation note: The present project was designed to investigate whether different levels of selenium and zinc alone and in combination in diet had any effect on the immune response of broiler chickens. For this purpose two hundred and twenty five day-old broiler chicks were taken and equally divided into three different trials i.e. A, B and C. Trial A was supplemented with selenium (Se) at four different rates 0.18, 0.5, 1.0 and 0.0 mg/kg in groups Al, A2, A3 and A4, respectively. Trial B was supplemented with zinc (Zn) at four different rates 40, 80, 120 an zero mg/kg in groups Bi, B2, B3 and B4, respectively. Trial C was supplemented with Se + Zn at rates of 0.18±40, 0.5±80, l.0±120 and 0.0±0 in groups Cl, C2, C3 and C4, respectively. Immunomodulatory effects o Se and Zn were evaluated by conducting hurnoral immune response against Newcastle disease vaccine (ND vaccine), delayed hypersensitivity reaction, weights of immune organs, growth traits and economy. Highest humoral immune response was observed in groups A3 (Se 1.0 mg/kg), B3 (Zn = 120 mg/kg), C3 (Se = 1.0 mg/kg + Zn = 120 mg/kg). rp1.e groups A4, B4 and 04 which were kept without Se and Zn supplementation had the lowest Immoral immune response. Delayed hypersensitivity index was highest in groups A3, B3 and C3, while lowest in control groups A4, B4 and C4. There was positive effect of Se and Zn on the histopathology of bursa of Fabricius, thyrnus and spleen. Body weight gains were also highest in A3, B3 and C3 and FCR was best in groups A3, B3 and C3. Weights of bursa of Fabricius, thymus and spleen were also highest in groups A3, B3 and C3, while lowest in the control groups A4, B4 and C4. On the whole immunomodulatory effects of supplementation of Se and Zn ir combination were better than individual supplementation of Se and Zn.
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The present project was designed to investigate whether different levels of selenium and zinc alone and in combination in diet had any effect on the immune response of broiler chickens. For this purpose two hundred and twenty five day-old broiler chicks were taken and equally divided into three different trials i.e. A, B and C. Trial A was supplemented with selenium (Se) at four different rates 0.18, 0.5, 1.0 and 0.0 mg/kg in groups Al, A2, A3 and A4, respectively. Trial B was supplemented with zinc (Zn) at four different rates 40, 80, 120 an zero mg/kg in groups Bi, B2, B3 and B4, respectively. Trial C was supplemented with Se + Zn at rates of 0.18±40, 0.5±80, l.0±120 and 0.0±0 in groups Cl, C2, C3 and C4, respectively. Immunomodulatory effects o Se and Zn were evaluated by conducting hurnoral immune response against Newcastle disease vaccine (ND vaccine), delayed hypersensitivity reaction, weights of immune organs, growth traits and economy. Highest humoral immune response was observed in groups A3 (Se 1.0 mg/kg), B3 (Zn = 120 mg/kg), C3 (Se = 1.0 mg/kg + Zn = 120 mg/kg). rp1.e groups A4, B4 and 04 which were kept without Se and Zn supplementation had the lowest Immoral immune response. Delayed hypersensitivity index was highest in groups A3, B3 and C3, while lowest in control groups A4, B4 and C4. There was positive effect of Se and Zn on the histopathology of bursa of Fabricius, thyrnus and spleen. Body weight gains were also highest in A3, B3 and C3 and FCR was best in groups A3, B3 and C3. Weights of bursa of Fabricius, thymus and spleen were also highest in groups A3, B3 and C3, while lowest in the control groups A4, B4 and C4.

On the whole immunomodulatory effects of supplementation of Se and Zn ir combination were better than individual supplementation of Se and Zn.

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