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Immunomodulatory Effects Of Multistrain Probiotic (Protexin)Tm On Broiler Chickens Vaccinated Against Infectious Bursal Disese Virus

By: Shamoon Nseem | Dr.Sameera Akhtar.
Contributor(s): Prof.Dr.Muhammad Akram Muneer | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 2002Subject(s): Department of MicrobiologyDDC classification: 0788,T Dissertation note: A project was conducted to study the immunomodulatory effects of multistrain probiotic (ProtexinTM) on broiler chickens vaccinated against infectious bursal disease virus. ProtexinTM was offered in feed to the broiler chickens from day 1 to day 49 of age. The parameters used to evaluate the effects of ProtexinTM on broiler chicks were body weight gain, FOR, weight of lymphoid organs such as bursa of Fabricius, thymus and spleen and immune response to IBDV vaccination, overall mortality and post virulent IBD challenge mortality and morbidity. The results showed that the ProtexinTM treated groups had high live body weight gain than the ProtexinTM non treated groups. Similarly, the feed conversion ratio of ProtexinTM treated groups was lower than the ProtexinTM non treated groups. The results showed that the ProtexinTM had no significant effect on the bursal body weight ratio, spleenic body weight ratio and thymic body weight ratio. The mean ELISA antibody titers of probiotic treated groups were significantly higher than that of chicken receiving no probiotic. No post challenge morbidity and mortality was recorded in ProtexinTM treated groups but negligible overall morbidity and mortality was recorded in ProtexinTM groups as compared to untreated groups% Furthermore, birds fed on probiotic (ProtexinTM) resulted in maximum profit and were proved economical.
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A project was conducted to study the immunomodulatory effects of multistrain probiotic (ProtexinTM) on broiler chickens vaccinated against infectious bursal disease virus. ProtexinTM was offered in feed to the broiler chickens from day 1 to day 49 of age. The parameters used to evaluate the effects of ProtexinTM on broiler chicks were body weight gain, FOR, weight of lymphoid organs such as bursa of Fabricius, thymus and spleen and immune response to IBDV vaccination, overall mortality and post virulent IBD challenge mortality and morbidity. The results showed that the ProtexinTM treated groups had high live body weight gain than the ProtexinTM non treated groups. Similarly, the feed conversion ratio of ProtexinTM treated groups was lower than the ProtexinTM non treated groups. The results showed that the ProtexinTM had no significant effect on the bursal body weight ratio, spleenic body weight ratio and thymic body weight ratio. The mean ELISA antibody titers of probiotic treated groups were significantly higher than that of chicken receiving no probiotic. No post challenge morbidity and mortality was recorded in ProtexinTM treated groups but negligible overall morbidity and mortality was recorded in ProtexinTM groups as compared to untreated groups% Furthermore, birds fed on probiotic (ProtexinTM) resulted in maximum profit and were proved economical.


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