Studies On The Cross Reactivity On Vaccinal Strains Of Infectious Bronchitis Virus
By: Bushra Zameer
| Dr.Khushi Muhammad.
Contributor(s): Dr.Khalid Saeed | Dr.Masood Rubani | Faculty of Veterinary Sciences.
Material type: 
BookPublisher: 2002Subject(s): Department of MicrobiologyDDC classification: 0801,T Dissertation note: Cross reactivity of four different strains of infectious bronchitis virus (D-274, D-1466, 4/91 and H-120) has been studied. All these strains induced stunting growth and increased volume of allanto-amniotic fluid (AAF). Killed oil based vaccine of each strain was prepared and used to produce hyperimmune serum in chickens. The hyperimmune serum was used in cross haemagglutination inhibition (HI) and cross neutralization tests.
The results of cross HI showed that D-274 and D-1466 shared 7.48% antigenic similarity with each other and H-120 sharedl3% and 8% antigenic similarities with D-274 and D-1466, respectively.
The results of cross Neutralization showed that no cross neutralization present among these virus strains. So vaccine having each strain is required to be used to control the problem.
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Thesis
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UVAS Library Thesis Section | Veterinary Science | 0801,T (Browse shelf) | Available | 0801,T |
Cross reactivity of four different strains of infectious bronchitis virus (D-274, D-1466, 4/91 and H-120) has been studied. All these strains induced stunting growth and increased volume of allanto-amniotic fluid (AAF). Killed oil based vaccine of each strain was prepared and used to produce hyperimmune serum in chickens. The hyperimmune serum was used in cross haemagglutination inhibition (HI) and cross neutralization tests.
The results of cross HI showed that D-274 and D-1466 shared 7.48% antigenic similarity with each other and H-120 sharedl3% and 8% antigenic similarities with D-274 and D-1466, respectively.
The results of cross Neutralization showed that no cross neutralization present among these virus strains. So vaccine having each strain is required to be used to control the problem.
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