The present study was designed to estimate the efficacy of different locally prepared anticoccidial vaccines against E. tenella infections i.e. irradiated non-sporulated vaccine and irradiated sporulated E. tenella vaccine, herbal anticoccidial (Coxigon) and cemical anlicoccidial (Suipha Diverdine). For estimation of the efficacy of the said anticoccidials, OPG counts, weight gain, FCR and mortality records were compared amongst the control and test groups.
A total of 150 day-old broilers were equally divided into six different groups on day 3 namely; A, B, C, D, E and F. Each group comprised of 25 chicks. ND vaccine was administered on day 1 and 21 of age to the chicks of all groups. rIhe test groups were infected through contamination of the bedding of the chicks by spraying sporulated oocysts between day 12 and 17 of the experinient. Group A acted as non-infected control, .13 as infected control, C was infected but vaccinated with irradiated non-sporulated E. tenella vaccine on day 3 and 10 @ 1000 oocysls per bird. Group D was infected and treated with Coxigon (herbal medicine), E was infected but treated with Coxidal (Sulpha diverdine). Similarly group F' was infected and vaccinated with irradiated but sporulated oocyst on day 3 and 10 @ 1000 oocysts per bird. To access the comparative efficucies of different groups mean OPG, mean weight gains and mean FCR of control and test groups were compared. The OPG counts were conducted on each 4th day from day 18th to 42. The results indicated that the first observation of OPG counts (day-18) showed heavy infection in all control (infected) and test groups. In group 13, 264523 oocysts were observed on day 18 which gradually reduced to 15773 on day 42. Group C (vaccinated with non sporulated, irradiated oocysts) showed 14214 OPG counts, which sharply declined on each observation and showed 89.00 QPG and day 38 followed by '0, by the end of the experiment, showing significaht difference from the control (1? <0.05). Group D (Coxigon) and groap E (Coxidar) showed gradual decline like infected control group and
735 OPG counts were observed in group E even on day 42. In group F the first observation showed 150428 OPG counts, which abruptly declined to 119 on day 38 followed by '0' on day 42. So group C and F' showed comparable and the best results as compared to groups D and E.
Weight gains were almost equal in all the test and control groups by day 14. The difference appeared on third observation (on day 21) between infected control and other groups. At the end of the experiment members of groups A, C, D, E and F gained 31%, 14%, 11.83%, 10.92% and 12% greater weights than group B. rphe FOR in ranked order was calculated in groups A, F, C, D, E and B, showing the cfCicacy of irradiated - sporulated vaccine. Mortalities occurred in groups B, C, D, E and F as 5, 2, 1, 4 and 1, respectively.