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Effect Of Virginiamycin And Zinc Bacitracin On New Castle Disease Virus Vaccinated Broiler Chicks

By: Muhammad Sohail Azhar | Prof.Dr. Muhamamd Akram Muneer.
Contributor(s): Dr. Mansur-ud-Din Ahmad | Faculty of Veterinary Sciences.
Material type: materialTypeLabelBookPublisher: 2005Subject(s): Department of MicrobiologyDDC classification: 0875,T Dissertation note: The project was designed to study the effects of Virginiamycin and Zinc bacitracin on Newcastle disease virus (NDV) vaccinated broilers. Two hundred broilers were divided into four groups comprising fifty in each. These groups were treated with Virginiamycin (Stafac-500), Zincbacitracin (Albac) and Cyclophosphamide at the dose rate of 20ppm/50kg, 25 gm/50kg and 0.3ml/bird, respectively. Effect of the treatments on weight gain, lymphoid organs and humoral immune response was evaluated. The virginiamycin treated group had higher body weight than the Zinc bacitracin and Cyclophosphamide treated or untreated control groups. Both virginiamycin and Zinc bacitracin treatments did not adversely affect the weights of bursa of Fabricius, spleen, thymus and liver of the birds. Cyclophosphamide treatment of birds in early life induced the bursal atrophy and slight depression in splenic weight gain. As compared to Cyclophosphamide treated and non-medicated control groups, the sera of virginiamycin / Zinc bacitracin treated groups had higher anti-NDV antibody titres at 42 days of age. The post-challenge sera of NDV vaccinated birds fed virginiamycin and Zinc bacitracin also had higher antibody titre as compared to NDV vaccinated Cyclophosphamide treated birds. The NDV vaccinated birds fed on virginiamycin / Zinc bacitracin medicated rations and those on non-medicated rations did not have any significant post-challenge mortality.
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The project was designed to study the effects of Virginiamycin and Zinc bacitracin on Newcastle disease virus (NDV) vaccinated broilers. Two hundred broilers were divided into four groups comprising fifty in each. These groups were treated with Virginiamycin (Stafac-500), Zincbacitracin (Albac) and Cyclophosphamide at the dose rate of 20ppm/50kg, 25 gm/50kg and 0.3ml/bird, respectively. Effect of the treatments on weight gain, lymphoid organs and humoral immune response was evaluated. The virginiamycin treated group had higher body weight than the Zinc bacitracin and Cyclophosphamide treated or untreated control groups. Both virginiamycin and Zinc bacitracin treatments did not adversely affect the weights of bursa of Fabricius, spleen, thymus and liver of the birds. Cyclophosphamide treatment of birds in early life induced the bursal atrophy and slight depression in splenic weight gain. As compared to Cyclophosphamide treated and non-medicated control groups, the sera of virginiamycin / Zinc bacitracin treated groups had higher anti-NDV antibody titres at 42 days of age. The post-challenge sera of NDV vaccinated birds fed virginiamycin and Zinc bacitracin also had higher antibody titre as compared to NDV vaccinated Cyclophosphamide treated birds. The NDV vaccinated birds fed on virginiamycin / Zinc bacitracin medicated rations and those on non-medicated rations did not have any significant post-challenge mortality.

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