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Evaluation Of The Effeet Of Different Modalities Of Vitiligo

By: Basit Zaheer | Prof.Dr.Muhammad Ashraf.
Contributor(s): Dr. Aftab | Dr. Aqeel Javeed.
Material type: materialTypeLabelBookPublisher: 2011Subject(s): Department of Pharmaoclogy & ToxicologyDDC classification: 1323,T Dissertation note: This study was conducted to find out the clinical pattern of Vitiligo in selected patients and to evaluate and compare the commonly used modalities for its treatment. All the patients with vitiligo presented to the Department of Dermatology Mayo Hospital, Lahore. A total of seventy patients were registered and followed-up for four months for repigmentation therapy. The present study was aimed to uncover the various expressions of melanocyte deficiencies in vitiligo In our people and to evaluate and compare the commonly used modalities for its treatment. No such study, comparing the psoralens with topical steroids at the same time was not done before. For repigmentation therapy patients were randomly divided into various treatment groups and me followed for the response for four months. The treatment groups included were PUVA (Psolarens Ultraviolet A), PUVASOL (Psolarens Ultraviolet from Sunlight), topical PUVA, Topical PUVASOL, topical steroids, systemic PUVA plus topical steroid and topical PUVA plus topical steroid. Two new modalities were included to find newer effective ways of treatment and their possible side effects. Complete repigmentation of the vitiligo without damage to the rest of the body was the goal of the treatment. Initial approach involved to make a definite diagnosis, psychological assistance and other supportive interventions such as use of camouflage cosmetics and sunscreens. The active treatment modalities that could be utilized included the topical use of potent steroids or photochemotherapy for atleast 2 months followed an assessment for response measurement. Novel interventions are required to increase patient compliance and a search for better treatment combinations.
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Thesis Thesis UVAS Library
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Veterinary Science 1323,T (Browse shelf) Available 1323,T
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This study was conducted to find out the clinical pattern of Vitiligo in selected patients and to
evaluate and compare the commonly used modalities for its treatment. All the patients with
vitiligo presented to the Department of Dermatology Mayo Hospital, Lahore. A total of seventy
patients were registered and followed-up for four months for repigmentation therapy. The
present study was aimed to uncover the various expressions of melanocyte deficiencies in
vitiligo In our people and to evaluate and compare the commonly used modalities for its
treatment. No such study, comparing the psoralens with topical steroids at the same time was not
done before.
For repigmentation therapy patients were randomly divided into various treatment groups and
me followed for the response for four months. The treatment groups included were PUVA
(Psolarens Ultraviolet A), PUVASOL (Psolarens Ultraviolet from Sunlight), topical PUVA,
Topical PUVASOL, topical steroids, systemic PUVA plus topical steroid and topical PUVA plus
topical steroid. Two new modalities were included to find newer effective ways of treatment and
their possible side effects. Complete repigmentation of the vitiligo without damage to the rest of
the body was the goal of the treatment. Initial approach involved to make a definite diagnosis,
psychological assistance and other supportive interventions such as use of camouflage cosmetics
and sunscreens. The active treatment modalities that could be utilized included the topical use of
potent steroids or photochemotherapy for atleast 2 months followed an assessment for response
measurement. Novel interventions are required to increase patient compliance and a search for
better treatment combinations.

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