Genetic Study Of Myp 2, Myp 15, Myp 16, And Myp 17, Loci Of Myopia In Families Of Province Punjab
By: Uzma Naureen
| Ms. Saeeda Kalsoom.
Contributor(s): Prof. Dr.Masroor Elahi Babar.
Material type: 
BookPublisher: 2011Subject(s): Institute of Biochemistry & BiotechnologyDDC classification: 1347,T Dissertation note: Myopia is said as the common cause of impaired vision and visual disability. In this disease the image is not focused sharply on the retina causing a dim vision to be formed and this condition of eye is referred as myopia. It is highly prevalent eye disease with its prevalence estimated to be I trillion throughout the
world and approximately [our billion in Pakistan. It is multi factorial disease and 19 loci identified up to date.
Eight myopic families were identified and selected for this study from different areas of Punjabprovince. Linkage analysis of these families was done by MYP 2, MYP J 5, MYP J 6 and MYP J 7 loci (each consisting of a set of 3 microsatellite markers) of myopia that were selected from the panel of 19 loci. A
total number of 12 microsatellite markers were used to analyze 40 samples from eight families. After DNA extraction and peR amplification, linkage analysis was carried out by gcnotyping through PAGE and haplotypes were constructed for the fami lies.
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Thesis
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UVAS Library Thesis Section | Veterinary Science | 1347,T (Browse shelf) | Available | 1347,T |
Myopia is said as the common cause of impaired vision and visual disability. In this disease the image is not focused sharply on the retina causing a dim vision to be formed and this condition of eye is referred as myopia. It is highly prevalent eye disease with its prevalence estimated to be I trillion throughout the
world and approximately [our billion in Pakistan. It is multi factorial disease and 19 loci identified up to date.
Eight myopic families were identified and selected for this study from different areas of Punjabprovince. Linkage analysis of these families was done by MYP 2, MYP J 5, MYP J 6 and MYP J 7 loci (each consisting of a set of 3 microsatellite markers) of myopia that were selected from the panel of 19 loci. A
total number of 12 microsatellite markers were used to analyze 40 samples from eight families. After DNA extraction and peR amplification, linkage analysis was carried out by gcnotyping through PAGE and haplotypes were constructed for the fami lies.
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