There are more than 200 million cattle in Pakistan which are a source of milk, meat, hide
and drought purpose. Due to this large population of cattle, Pakistan is the fourth largest milk
producer in the world. In spite of large number of cattle population in Pakistan, per animal milk
production is yet quite low. That's why it is not wrong to say that there is still a great potential in
the dairy sector of Pakistan to improve the overall milk production by improving the per animal
Jilk production. This can be only achieved by improving the genetics of the dairy animals in
Pakistan besides the other factors as well. Milk production is a polygenic trait. It is well
established that growth hormone (GH) released from pituitary gland also plays an essential role'
in growth, mammary gland development and lactation process. POUIFI factor is a member of
the POU family of transcription factors that regulate animal growth and development and is also
involved in the development of pituitary and regulation of hormonal expressions in animals.
Therefore, genetic variation in the POU1Fl gene and its associations with growth traits in
livestock animals could provide useful genetic markers for animal selection and breeding
through marker-assisted selection (MAS). This study was conducted to genetically characterize
!he POUIFI gene to identify the SNPs as genetic markers for future breeding and selection
~Ians. Keeping in view the importance of this gene all introns and axons were sequenced in
smples of Red sindhi and Dhanni cattle to identify the SNP and validate the potential markers
There are more than 200 million cattle in Pakistan which are a source of milk, meat, hide
and drought purpose. Due to this large population of cattle, Pakistan is the fourth largest milk
producer in the world. In spite of large number of cattle population in Pakistan, per animal milk
production is yet quite low. That's why it is not wrong to say that there is still a great potential in
the dairy sector of Pakistan to improve the overall milk production by improving the per animal
Jilk production. This can be only achieved by improving the genetics of the dairy animals in
Pakistan besides the other factors as well. Milk production is a polygenic trait. It is well
established that growth hormone (GH) released from pituitary gland also plays an essential role'
in growth, mammary gland development and lactation process. POUIFI factor is a member of
the POU family of transcription factors that regulate animal growth and development and is also
involved in the development of pituitary and regulation of hormonal expressions in animals.
Therefore, genetic variation in the POU1Fl gene and its associations with growth traits in
livestock animals could provide useful genetic markers for animal selection and breeding
through marker-assisted selection (MAS). This study was conducted to genetically characterize
!he POUIFI gene to identify the SNPs as genetic markers for future breeding and selection
~Ians. Keeping in view the importance of this gene all introns and axons were sequenced in
smples of Red sindhi and Dhanni cattle to identify the SNP and validate the potential markers