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Prevalence Of Lactose Intolerance Among The Students Of The University Of Veterinary And Animal Sciences

By: Anam Aman | Dr. Sanaullah Iqbal.
Contributor(s): Dr. Muhammad Nasir | Prof. Dr.
Material type: materialTypeLabelBookPublisher: 2013Subject(s): Department of Food Sciences & HumanDDC classification: 1780,T Dissertation note: Lactose is milk sugar. It is found in milk and dairy products. Lactase (Betagalactosidase lactase-phlorizin hydrolase) is the enzyme present in the enterocytes of small intestinal brush border and it is responsible for the breakdown of lactose into its monosaccharide components glucose and galactose that are absorbed into the bloodstream. Lactasedeficiency leads to lactose mal-absorption and resulting gastrointestinal symptoms of intolerance.Lactose intolerance is defined by symptoms of mal-absorption such as abdominal pain,bloating, distention, flatulence and diarrhea due to partial digestion of lactose. This study was conducted in following phases. Lactose intolerance test was performed to diagnose lactose intolerance. In 1st phase lactose solution was prepared by dissolving 25grams of synthetic lactose in 250ml water and in this way 10% lactose solution was prepared and fasting blood glucose level of students was recorded first by using Glucometer. During 2nd phase lactose solution was given to each student and time was noted.During 3rd phase after giving lactose dose blood glucose level of each student was recorded at 30, 60 minutes. Test was consider positive ifafter lactose solution dose the rise in fasting blood glucose level was less than 20mg per deciliter and if rise in fasting blood glucose level was more than 30mg per dl within 1 hour of lactose solution consumption, test was considered negative. If rise in blood glucose level was between 20 and 30mg/dl then on the basis of sign and symptoms of intolerance, it was decided either a person was lactose intolerant or not. According to the criteria mentioned above significant outcomes of the present research are summarized as following: Out of 300(100.0) %, 213(71.0) % had positive lactose intolerance test and 87(29.0) % had negative lactose intolerance test.This study determined that prevalence of lactose intolerance in the UVAS, Lahore students was 71.0%. Correlation of lactose intolerance with gender, age, height, BMI, dietary food preferences was determined using chi square test and Phi Cramer's V, p value was considered significant at p <0.05. Chi square results were significant for age, height and weight. On the basis of finding of this study it can be stated that prevalence of lactose intolerance increases with increase in age, increase in weight and height.Chi square results were insignificant for gender, BMI and dietary food preferences, so prevalence of lactose intolerance is independent entity for gender, BMI and dietary food preferences. Chi square test of independence was calculated comparing the frequency of lactose intolerance for dietary food preferences of subjects. No-significant relationship was found, X2 (2) =3.696, p = 0.158, so p >0.05. There was no correlation between the dietary food preferences of subjects and the lactose intolerance. Phi Cramer's V was used to determine strength of association between lactose intolerance anddietary food preferences of subjects.No significant relationship was found between frequencies of lactose intolerance dietary food preferences.Phi=0-.111, Cramer's V=0.111,p >0.05 There was no difference in results of the dietary food preferences of subjects and the prevalence of lactose intolerance and we can conclude that people who consumed milk products compared to those who did not consume milk/ milk products were equally affected by lactose intolerance as the non-milk product consumers and use of lactose containing milk products does not affect the prevalence of genetically inhered hypolactasia and this is in accordance with Troelsen (2005) findings, Enattah et al. (2002) findings on adult-type hypolactasia and also in accordance with Lisker et al. (1975) and Sahi et al. (1973) findings on recessive inheritance of adult type of intestinal lactase deficiency and recessive inheritance of adult-type lactose malabsorption respectively.
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Veterinary Science 1780,T (Browse shelf) Available 1780,T
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Lactose is milk sugar. It is found in milk and dairy products. Lactase (Betagalactosidase lactase-phlorizin hydrolase) is the enzyme present in the enterocytes of small intestinal brush border and it is responsible for the breakdown of lactose into its monosaccharide components glucose and galactose that are absorbed into the bloodstream. Lactasedeficiency leads to lactose mal-absorption and resulting gastrointestinal symptoms of intolerance.Lactose intolerance is defined by symptoms of mal-absorption such as abdominal pain,bloating, distention, flatulence and diarrhea due to partial digestion of lactose. This study was conducted in following phases. Lactose intolerance test was performed to diagnose lactose intolerance. In 1st phase lactose solution was prepared by dissolving 25grams of synthetic lactose in 250ml water and in this way 10% lactose solution was prepared and fasting blood glucose level of students was recorded first by using Glucometer. During 2nd phase lactose solution was given to each student and time was noted.During 3rd phase after giving lactose dose blood glucose level of each student was recorded at 30, 60 minutes.
Test was consider positive ifafter lactose solution dose the rise in fasting blood glucose level was less than 20mg per deciliter and if rise in fasting blood glucose level was more than 30mg per dl within 1 hour of lactose solution consumption, test was considered negative. If rise in blood glucose level was between 20 and 30mg/dl then on the basis of sign and symptoms of intolerance, it was decided either a person was lactose intolerant or not. According to the criteria mentioned above significant outcomes of the present research are summarized as following:
Out of 300(100.0) %, 213(71.0) % had positive lactose intolerance test and 87(29.0) % had negative lactose intolerance test.This study determined that prevalence of lactose intolerance in the UVAS, Lahore students was 71.0%. Correlation of lactose intolerance with gender, age, height, BMI, dietary food preferences was determined using chi square test and Phi Cramer's V, p value was considered significant at p <0.05. Chi square results were significant for age, height and weight. On the basis of finding of this study it can be stated that prevalence of lactose intolerance increases with increase in age, increase in weight and height.Chi square results were insignificant for gender, BMI and dietary food preferences, so prevalence of lactose intolerance is independent entity for gender, BMI and dietary food preferences.
Chi square test of independence was calculated comparing the frequency of lactose intolerance for dietary food preferences of subjects. No-significant relationship was found, X2 (2) =3.696, p = 0.158, so p >0.05. There was no correlation between the dietary food preferences of subjects and the lactose intolerance. Phi Cramer's V was used to determine strength of association between lactose intolerance anddietary food preferences of subjects.No significant relationship was found between frequencies of lactose intolerance dietary food preferences.Phi=0-.111, Cramer's V=0.111,p >0.05
There was no difference in results of the dietary food preferences of subjects and the prevalence of lactose intolerance and we can conclude that people who consumed milk products compared to those who did not consume milk/ milk products were equally affected by lactose intolerance as the non-milk product consumers and use of lactose containing milk products does not affect the prevalence of genetically inhered hypolactasia and this is in accordance with Troelsen (2005) findings, Enattah et al. (2002) findings on adult-type hypolactasia and also in accordance with Lisker et al. (1975) and Sahi et al. (1973) findings on recessive inheritance of adult type of intestinal lactase deficiency and recessive inheritance of adult-type lactose malabsorption respectively.

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