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Comparative Efficacy Of Chemical And Surgical Debridement For Management Of Proud Flesh In Equines

By: Assad Moon (2008-VA-187) | Prof. Dr. Muhammad Arif Khan.
Contributor(s): Dr. Shahla Gul Bukhari | Dr. Muhammad Ijaz.
Material type: materialTypeLabelBookPublisher: 2015Description: 75p.Subject(s): Department of Clinical SurgeryDDC classification: 2413-T Dissertation note: Wound healing in equines is one of the most laborious and expensive challenge to all stud farmers and surgeons. Exuberant granulation typically is an irregular and unhealthy appearing tissue with many grooves and clefts. Histologically exuberant granulation tissue has remains of fibrin deposits, which have not been cleared by the acute inflammatory response. Horses are predisposed to trauma wounds that can be labour intensive and expensive to manage. Wounds localized at the trunk region are less problematic and heal faster than wounds located at the distal aspect of the limb. Complications such as wound infection, formation of exuberant granulation tissue (EGT) and hypertrophic scarring are frequent. The EGT or “Proud Flesh” is considered similar to the keloid of the human skin and together with wound contamination/infection, is currently the most complicated aspect of wound management in equines. The present project was designed to evaluate comparative efficacy of surgical and chemical debridement of such kind of wounds in horses. The clinical study was conducted on 20 already traumatized horses of either sex. The animals were divided into four groups (I, II, III and IV) comprising five animals each. These animals were kept in S.P.C.A, University of Veterinary and Animal Sciences, Lahore. In a group I, Surgical excision was carried out to remove excessive growth from wounded area. Local anaesthesia with two percent lignocaine was in filtered for removal. Antiseptics were applied and over-granulation was smoothly removed from one margin of skin to other. Group II animals were treated with ten percent copper sulphate ointment, Group III animals were treated with two percent silver nitrate ointment and Group IV animals were treated with white lotion. Each technique had its own advantages and disadvantages. The results proved that surgical removal was a best choice for management of hyper-granulated wounds. It also had good scar formation SUMMARY 72 and faster recovery as compared to other chemical agents. It allows the closure of large wounds and faster epithelization to margins. The results of present study clearly indicated that surgical excision of hyper-granulated wound on early stages yields good recovery and proper union. Although silver nitrate has better penetrating power in wounds but it has no ability to epithelize the wound which terminates in slow recovery. Moreover silver is an expensive and less affordable to a common man. Copper sulphate has good recovery but it causes irritation while application and animal feels pain. White lotion is one of the good choice but expensive.
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Wound healing in equines is one of the most laborious and expensive challenge to all stud farmers and surgeons. Exuberant granulation typically is an irregular and unhealthy appearing tissue with many grooves and clefts. Histologically exuberant granulation tissue has remains of fibrin deposits, which have not been cleared by the acute inflammatory response. Horses are predisposed to trauma wounds that can be labour intensive and expensive to manage. Wounds localized at the trunk region are less problematic and heal faster than wounds located at the distal aspect of the limb. Complications such as wound infection, formation of exuberant granulation tissue (EGT) and hypertrophic scarring are frequent. The EGT or “Proud Flesh” is considered similar to the keloid of the human skin and together with wound contamination/infection, is currently the most complicated aspect of wound management in equines. The present project was designed to evaluate comparative efficacy of surgical and chemical debridement of such kind of wounds in horses. The clinical study was conducted on 20 already traumatized horses of either sex. The animals were divided into four groups (I, II, III and IV) comprising five animals each. These animals were kept in S.P.C.A, University of Veterinary and Animal Sciences, Lahore. In a group I, Surgical excision was carried out to remove excessive growth from wounded area. Local anaesthesia with two percent lignocaine was in filtered for removal. Antiseptics were applied and over-granulation was smoothly removed from one margin of skin to other. Group II animals were treated with ten percent copper sulphate ointment, Group III animals were treated with two percent silver nitrate ointment and Group IV animals were treated with white lotion. Each technique had its own advantages and disadvantages. The results proved that surgical removal was a best choice for management of hyper-granulated wounds. It also had good scar formation
SUMMARY
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and faster recovery as compared to other chemical agents. It allows the closure of large wounds and faster epithelization to margins.
The results of present study clearly indicated that surgical excision of hyper-granulated wound on early stages yields good recovery and proper union. Although silver nitrate has better penetrating power in wounds but it has no ability to epithelize the wound which terminates in slow recovery. Moreover silver is an expensive and less affordable to a common man. Copper sulphate has good recovery but it causes irritation while application and animal feels pain. White lotion is one of the good choice but expensive.

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