Study Of Prescribing Trends And Evaluation Of Therapeutic Effectiveness Of Prescribed Medications For Type 2 Diabetes Mellitus In Tertiary Care Hospital Of Lahore, Pakistan
By: Bareera Rana (2008-VA-545)
| Allah Bukhsh Awan.
Contributor(s): Muhammad Faisal Nadeem | Dr. Muhammad Ovais Omer.
Material type: 
BookPublisher: 2015Description: 44p.Subject(s): Department of PharmaceuticsDDC classification: 2427-T Dissertation note: Diabetes mellitus is metabolic disorder resulting from decrease in insulin secretion and insulin action or both. Presently, the prevalence of diabetes is 8.3% and 7.89% in world and in Pakistan, respectively. Pakistan is ranked 7th in diabetes mellitus prevalence making it a major problem in our health care system. The study was based on the prescribing trends and evaluation of therapeutic effectiveness of oral hypoglycemic agents in tertiary care hospital of Lahore. A concurrent observational study of 3 months duration was performed in diabetes management centre of a tertiary care hospital of Lahore under the supervision of an endocrinologist. Socio-demographic data and compliance levels were determined by questionnaire while hyperglycemic control was analyzed by continuous monitoring of HbA1c at the start and the end of the study. Data was finally analyzed by descriptive statistics and SPSS 16. The study demonstrated that the most frequently prescribed oral hypoglycemic agent was metformin which is in accordance with the guidelines, however individualization of treatment is required keeping in view the patient factors respectively. Intensification of current treatment for patients with higher HbA1c values is needed. Data regarding therapeutic effectiveness of the hypoglycemic agents shows that the hypoglycemic agents were effective enough to lower HbA1c values to bring it to normal values but patient factors of non-compliance and not following life style modification patterns are not allowing the values to come up to the mark, that is, the decrease in HbA1c values according to guidelines within three months of the treatment. Presently it is the need of time to run educational awareness programs for awareness regarding diabetes among people to made them know about life style interventions. Moreover the prescribing trends and their relevance with glycemic control must also be documented. It will generate data for knowing which trend of prescribing is producing better results and whether the trends are meeting international standards or not.
| Item type | Current location | Collection | Call number | Status | Date due | Barcode | Item holds |
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Thesis
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UVAS Library Thesis Section | Veterinary Science | 2427-T (Browse shelf) | Available | 2427-T |
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Diabetes mellitus is metabolic disorder resulting from decrease in insulin secretion and insulin action or both. Presently, the prevalence of diabetes is 8.3% and 7.89% in world and in Pakistan, respectively. Pakistan is ranked 7th in diabetes mellitus prevalence making it a major problem in our health care system. The study was based on the prescribing trends and evaluation of therapeutic effectiveness of oral hypoglycemic agents in tertiary care hospital of Lahore. A concurrent observational study of 3 months duration was performed in diabetes management centre of a tertiary care hospital of Lahore under the supervision of an endocrinologist. Socio-demographic data and compliance levels were determined by questionnaire while hyperglycemic control was analyzed by continuous monitoring of HbA1c at the start and the end of the study. Data was finally analyzed by descriptive statistics and SPSS 16. The study demonstrated that the most frequently prescribed oral hypoglycemic agent was metformin which is in accordance with the guidelines, however individualization of treatment is required keeping in view the patient factors respectively. Intensification of current treatment for patients with higher HbA1c values is needed. Data regarding therapeutic effectiveness of the hypoglycemic agents shows that the hypoglycemic agents were effective enough to lower HbA1c values to bring it to normal values but patient factors of non-compliance and not following life style modification patterns are not allowing the values to come up to the mark, that is, the decrease in HbA1c values according to guidelines within three months of the treatment. Presently it is the need of time to run educational awareness programs for awareness regarding diabetes among people to made them know about life style interventions. Moreover the prescribing trends and their relevance with glycemic control must also be documented. It will generate data for knowing which trend of prescribing is producing better results and whether the trends are meeting international standards or not.
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